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rs10941679

From SNPedia

Orientationplus
Stabilizedplus
Make rs10941679(A;A)
Make rs10941679(A;G)
Make rs10941679(G;G)
ReferenceGRCh38 38.1/141
Chromosome5
Position44706396
is asnp
is mentioned by
dbSNPrs10941679
ebirs10941679
HLIrs10941679
Exacrs10941679
Varsomers10941679
Maprs10941679
PheGenIrs10941679
hapmaprs10941679
1000 genomesrs10941679
hgdprs10941679
ensemblrs10941679
gopubmedrs10941679
geneviewrs10941679
scholarrs10941679
googlers10941679
pharmgkbrs10941679
gwascentralrs10941679
openSNPrs10941679
23andMers10941679
23andMe allrs10941679
SNP Nexus

SNPshotrs10941679
SNPdbers10941679
MSV3drs10941679
GWAS Ctlgrs10941679
GMAF0.3007
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs4415084 and rs10941679 confer risk for estrogen receptor breast cancer (ER)-positive tumors (OR = 1.27, P = 2.5E-12 for rs10941679) based on a study of 6,145 cases.

[PMID 18438407]

OMIM114480
DescBREAST CANCER
Variant
Relatedalso
[PMID 20095854OA-icon.png] Novel Breast Cancer Risk Alleles and Interaction with Ionizing Radiation among U.S. Radiologic Technologists


[PMID 20140701OA-icon.png] Genetic variants on chromosome 5p12 are associated with risk of breast cancer in African American women: the Black Women's Health Study


[PMID 20699374OA-icon.png] Evaluation of Breast Cancer Susceptibility Loci in Chinese Women

[PMID 21118973OA-icon.png] Common Breast Cancer Susceptibility Alleles and the Risk of Breast Cancer for BRCA1 and BRCA2 Mutation Carriers: Implications for Risk Prediction


[PMID 21791674OA-icon.png] Interactions Between Genetic Variants and Breast Cancer Risk Factors in the Breast and Prostate Cancer Cohort Consortium


[PMID 21795498OA-icon.png] Confirmation of 5p12 as a susceptibility locus for progesterone-receptor-positive, lower grade breast cancer


[PMID 21795501OA-icon.png] Replication of breast cancer GWAS susceptibility loci in the Women's Health Initiative African American SHARe study


[PMID 22832384] Genetic variants at 5p12 and risk of breast cancer in Han Chinese

[PMID 19088016OA-icon.png] Genetic susceptibility loci for breast cancer by estrogen receptor status.

[PMID 19232126OA-icon.png] Association between breast cancer susceptibility loci and mammographic density: the Multiethnic Cohort.

[PMID 19330030OA-icon.png] A multistage genome-wide association study in breast cancer identifies two new risk alleles at 1p11.2 and 14q24.1 (RAD51L1).

[PMID 19567422OA-icon.png] Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042.

[PMID 20146796OA-icon.png] Familial relative risks for breast cancer by pathological subtype: a population-based cohort study.

[PMID 20484103OA-icon.png] Genetic and clinical predictors for breast cancer risk assessment and stratification among Chinese women.

[PMID 22532573OA-icon.png] The role of genetic breast cancer susceptibility variants as prognostic factors.


GET Evidence
rs10941679
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.242188
summary



[PMID 23221726OA-icon.png] Gene-Environment Interactions for Breast Cancer Risk Among Chinese Women: A Report From the Shanghai Breast Cancer Genetics Study


[PMID 23479381] Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan


[PMID 23704029] Breast cancer susceptibility loci in association with age at menarche, age at natural menopause and the reproductive lifespan

GWAS snp
PMID [PMID 23535729OA-icon.png]
Trait Breast cancer
Title Large-scale genotyping identifies 41 new loci associated with breast cancer risk.
Risk Allele G
P-val 2E-37
Odds Ratio 1.13 [1.10-1.15]


[PMID 24528085] Breast Cancer Association Studies in a Han Chinese Population using 10 European-ancestry-associated Breast Cancer Susceptibility SNPs


[PMID 26070784OA-icon.png] Genetic risk variants associated with in situ breast cancer


[PMID 27640304] Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.


[PMID 27732943] Angiotensin II Receptor 1 gene variants are associated with high-altitude pulmonary edema risk.