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rs11031006

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.5 slightly lower odds of giving birth to fraternal twins
(A;G) 1.5 slightly lower odds of giving birth to fraternal twins
(G;G) 1.5 Most common genotype; slightly higher odds of giving birth to fraternal twins
ReferenceGRCh38.p2 38.2/147
Chromosome11
Position30204981
GeneLOC105376607
is asnp
is mentioned by
dbSNPrs11031006
ebirs11031006
HLIrs11031006
Exacrs11031006
Varsomers11031006
Maprs11031006
PheGenIrs11031006
hapmaprs11031006
1000 genomesrs11031006
hgdprs11031006
ensemblrs11031006
gopubmedrs11031006
geneviewrs11031006
scholarrs11031006
googlers11031006
pharmgkbrs11031006
gwascentralrs11031006
openSNPrs11031006
23andMers11031006
23andMe allrs11031006
SNP Nexus

SNPshotrs11031006
SNPdbers11031006
MSV3drs11031006
GWAS Ctlgrs11031006
Max Magnitude1.5
? (A;A) (A;G) (G;G) 28
A meta-analysis found that the most common allele for this SNP, rs11031006(G), is actually associated with a slightly higher likelihood of giving birth to fraternal (dizygotic) twins (odds ratio 1.41, CI:1.29–1.53, p= 1.54 × 10e−9) compared to carriers of the (A) allele. A subsequent replication study of Icelanders yielded lower odds (1.14, CI:1.06–1.22,p=3 × 10e−3).

http://www.cell.com/ajhg/abstract/S0002-9297%2816%2930043-X Identification of Common Genetic Variants Influencing Spontaneous Dizygotic Twinning and Female Fertility