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rs11065987

From SNPedia

Orientationplus
Stabilizedplus
Make rs11065987(A;A)
Make rs11065987(A;G)
Make rs11065987(G;G)
ReferenceGRCh38 38.1/141
Chromosome12
Position111634620
is asnp
is mentioned by
dbSNPrs11065987
ebirs11065987
HLIrs11065987
Exacrs11065987
Varsomers11065987
Maprs11065987
PheGenIrs11065987
hapmaprs11065987
1000 genomesrs11065987
hgdprs11065987
ensemblrs11065987
gopubmedrs11065987
geneviewrs11065987
scholarrs11065987
googlers11065987
pharmgkbrs11065987
gwascentralrs11065987
openSNPrs11065987
23andMers11065987
23andMe allrs11065987
SNP Nexus

SNPshotrs11065987
SNPdbers11065987
MSV3drs11065987
GWAS Ctlgrs11065987
GMAF0.1965
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19862010OA-icon.png]
Trait Hematocrit
Title Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium
Risk Allele G
P-val 1E-12
Odds Ratio 0.17 [0.12-0.22] % decrease
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele G
P-val 2E-9
Odds Ratio 0.9700 None


[PMID 21193429OA-icon.png] Determinants of platelet count in humans.


GET Evidence
rs11065987
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.195312
summary



Babies who are rs11065987(G;G) are about 1.3 times more likely to be born with tetralogy of Fallot (TOF) http://blog.23andme.com/23andme-research/snpwatch/snpwatch-common-genetic-factors-associated-with-blue-babies/

GWAS snp
PMID [PMID 23297363OA-icon.png]
Trait Tetralogy of Fallot
Title Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot.
Risk Allele G
P-val 8E-11
Odds Ratio 1.34 [1.208-1.496]
GWAS snp
PMID [PMID 24262325OA-icon.png]
Trait Coronary artery disease or ischemic stroke
Title Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
Risk Allele
P-val 4E-14
Odds Ratio NR NR
GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait Cholesterol, total
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele G
P-val 2E-16
Odds Ratio .03 [NR] unit decrease