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rs1113132

From SNPedia

Orientationminus
Stabilizedminus
Make rs1113132(C;C)
Make rs1113132(C;G)
Make rs1113132(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position44231853
GeneEXT2
is asnp
is mentioned by
dbSNPrs1113132
ebirs1113132
HLIrs1113132
Exacrs1113132
Varsomers1113132
Maprs1113132
PheGenIrs1113132
hapmaprs1113132
1000 genomesrs1113132
hgdprs1113132
ensemblrs1113132
gopubmedrs1113132
geneviewrs1113132
scholarrs1113132
googlers1113132
pharmgkbrs1113132
gwascentralrs1113132
openSNPrs1113132
23andMers1113132
23andMe allrs1113132
SNP Nexus

SNPshotrs1113132
SNPdbers1113132
MSV3drs1113132
GWAS Ctlgrs1113132
GMAF0.2865
Max Magnitude
? (C;C) (C;G) (G;G) 28
Rs1113132
PubMed [PMID 17293876]
Affy Probeset SNP_A-2152927
Affy Orientation reverse
On GW 5.0 1
Alleles A/B C/G
Ancestral C
Population CEU
Allele C
Case Freq. 0.76
Control Freq. 0.73
Odds Ratio Het 1.15
Odds Ratio Hom 1.36
Odds Ratio All
Disease Type II Diabetes (T2D)


rs1113132 increases susceptibility to Type II Diabetes 1.15 times for heterozygotes (CG) and 1.36 times for homozygotes (CC) [PMID 17293876]


[PMID 17786204OA-icon.png] Polymorphisms within novel risk loci for type 2 diabetes determine beta-cell function.


[PMID 18162508] Association of CDKAL1, IGF2BP2, CDKN2A/B, HHEX, SLC30A8, and KCNJ11 with susceptibility to type 2 diabetes in a Japanese population.


[PMID 18443202OA-icon.png] Association analysis in african americans of European-derived type 2 diabetes single nucleotide polymorphisms from whole-genome association studies.


[PMID 18461161OA-icon.png] Post genome-wide association studies of novel genes associated with type 2 diabetes show gene-gene interaction and high predictive value.


[PMID 18544707OA-icon.png] Extension of type 2 diabetes genome-wide association scan results in the diabetes prevention program.


[PMID 18633108OA-icon.png] Common variants in CDKAL1, CDKN2A/B, IGF2BP2, SLC30A8, and HHEX/IDE genes are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.


[PMID 19008344OA-icon.png] Association analysis of variation in/near FTO, CDKAL1, SLC30A8, HHEX, EXT2, IGF2BP2, LOC387761, and CDKN2B with type 2 diabetes and related quantitative traits in Pima Indians.


[PMID 22377712] Association between type 2 diabetes genetic susceptibility loci and visceral and subcutaneous fat area as determined by computed tomography.


[PMID 23052945] Association between variants of EXT2 and type 2 diabetes: a replication and meta-analysis


[PMID 23458876] ACE I/D and MTHFR C677T polymorphisms are significantly associated with type 2 diabetes in Arab ethnicity: a meta-analysis.


[PMID 25207843] Impact of variants of the EXT2 gene on Type 2 diabetes and its related traits in the Chinese han population