Have questions? Visit https://www.reddit.com/r/SNPedia

rs11218343

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(T;T) 0
Make rs11218343(C;C)
Make rs11218343(C;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position121564878
GeneSORL1
is asnp
is mentioned by
dbSNPrs11218343
ebirs11218343
HLIrs11218343
Exacrs11218343
Varsomers11218343
Maprs11218343
PheGenIrs11218343
hapmaprs11218343
1000 genomesrs11218343
hgdprs11218343
ensemblrs11218343
gopubmedrs11218343
geneviewrs11218343
scholarrs11218343
googlers11218343
pharmgkbrs11218343
gwascentralrs11218343
openSNPrs11218343
23andMers11218343
23andMe allrs11218343
SNP Nexus

SNPshotrs11218343
SNPdbers11218343
MSV3drs11218343
GWAS Ctlgrs11218343
GMAF0.1198
Max Magnitude0
? (C;C) (C;T) (T;T) 28


GET Evidence
rs11218343
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.117188
summary



GWAS snp
PMID [PMID 23565137OA-icon.png]
Trait Alzheimer's disease (late onset)
Title SORL1 is genetically associated with late-onset Alzheimer's disease in Japanese, Koreans and Caucasians.
Risk Allele
P-val 2E-9
Odds Ratio 1.23 [1.15-1.33]
GWAS snp
PMID [PMID 24162737OA-icon.png]
Trait Alzheimer's disease (late onset)
Title Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.
Risk Allele T
P-val 1E-14
Odds Ratio 1.30 [1.22-1.39]


[PMID 26543236] Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population