Have questions? Visit https://www.reddit.com/r/SNPedia

rs1126671

From SNPedia

Orientationminus
Stabilizedminus
Make rs1126671(A;A)
Make rs1126671(A;G)
Make rs1126671(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position99127263
GeneADH4, SLC3A1
is asnp
is mentioned by
dbSNPrs1126671
ebirs1126671
HLIrs1126671
Exacrs1126671
Varsomers1126671
Maprs1126671
PheGenIrs1126671
hapmaprs1126671
1000 genomesrs1126671
hgdprs1126671
ensemblrs1126671
gopubmedrs1126671
geneviewrs1126671
scholarrs1126671
googlers1126671
pharmgkbrs1126671
gwascentralrs1126671
openSNPrs1126671
23andMers1126671
23andMe allrs1126671
SNP Nexus

SNPshotrs1126671
SNPdbers1126671
MSV3drs1126671
GWAS Ctlgrs1126671
GMAF0.18
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 19925625] Cluster Headache is Associated With the Alcohol Dehydrogenase 4 (ADH4) Gene


[PMID 16220108] ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies.


[PMID 16685648OA-icon.png] Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence.


[PMID 17069770OA-icon.png] Personality traits of agreeableness and extraversion are associated with ADH4 variation.


[PMID 17185388OA-icon.png] Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans.


[PMID 17273965OA-icon.png] Evidence of positive selection on a class I ADH locus.


[PMID 18331377OA-icon.png] Association of ADH and ALDH genes with alcohol dependence in the Irish Affected Sib Pair Study of alcohol dependence (IASPSAD) sample.


[PMID 19193628OA-icon.png] ADH single nucleotide polymorphism associations with alcohol metabolism in vivo.


[PMID 19298322OA-icon.png] Associations and interactions between SNPs in the alcohol metabolizing genes and alcoholism phenotypes in European Americans.


GET Evidence
ADH4-I309V
aa_change Ile309Val
aa_change_short I309V
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.73192
summary