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rs1138272

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs1138272(C;T)
Make rs1138272(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position67586108
GeneGSTP1
is asnp
is mentioned by
dbSNPrs1138272
ebirs1138272
HLIrs1138272
Exacrs1138272
Varsomers1138272
Maprs1138272
PheGenIrs1138272
hapmaprs1138272
1000 genomesrs1138272
hgdprs1138272
ensemblrs1138272
gopubmedrs1138272
geneviewrs1138272
scholarrs1138272
googlers1138272
pharmgkbrs1138272
gwascentralrs1138272
openSNPrs1138272
23andMers1138272
23andMe allrs1138272
SNP Nexus

SNPshotrs1138272
SNPdbers1138272
MSV3drs1138272
GWAS Ctlgrs1138272
GMAF0.03535
Max Magnitude0
? (C;C) (C;T) (T;T) 28
[PMID 21914837OA-icon.png] Childhood brain tumors and maternal cured meat consumption in pregnancy: differential effect by glutathione S-transferases


[PMID 17160896OA-icon.png] Orofacial cleft risk is increased with maternal smoking and specific detoxification-gene variants.


[PMID 17194543OA-icon.png] Glutathione S-transferase mu, omega, pi, and theta class variants and smoking in Parkinson's disease.


[PMID 17601350OA-icon.png] A genetic association analysis of cognitive ability and cognitive ageing using 325 markers for 109 genes associated with oxidative stress or cognition.


[PMID 17686149OA-icon.png] Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery.


[PMID 18191955OA-icon.png] Correlating observed odds ratios from lung cancer case-control studies to SNP functional scores predicted by bioinformatic tools.


[PMID 18559526OA-icon.png] Glutathione s-transferase p1: gene sequence variation and functional genomic studies.


[PMID 18601742OA-icon.png] Polymorphisms of selected xenobiotic genes contribute to the development of papillary thyroid cancer susceptibility in Middle Eastern population.


[PMID 18709160OA-icon.png] Interactions between glutathione S-transferase P1, tumor necrosis factor, and traffic-related air pollution for development of childhood allergic disease.


[PMID 18776599OA-icon.png] Susceptibility genes for gentamicin-induced vestibular dysfunction.


[PMID 18854777OA-icon.png] Germline genetic variations in drug action pathways predict clinical outcomes in advanced lung cancer treated with platinum-based chemotherapy.


[PMID 18992148OA-icon.png] Low-penetrance alleles predisposing to sporadic colorectal cancers: a French case-controlled genetic association study.


[PMID 20049130OA-icon.png] Black carbon exposure, oxidative stress genes, and blood pressure in a repeated-measures study.


[PMID 20459744OA-icon.png] Cyclophosphamide-metabolizing enzyme polymorphisms and survival outcomes after adjuvant chemotherapy for node-positive breast cancer: a retrospective cohort study.


[PMID 20540773OA-icon.png] The 341C/T polymorphism in the GSTP1 gene is associated with increased risk of oesophageal cancer.


[PMID 21741876] Polymorphisms in tobacco metabolism and DNA repair genes modulate oral precancer and cancer risk.


[PMID 22661588OA-icon.png] Antioxidant enzyme polymorphisms and neuropsychological outcomes in medulloblastoma survivors: a report from the Childhood Cancer Survivor Study.


GET Evidence
GSTP1-A114V
aa_change Ala114Val
aa_change_short A114V
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0617956
summary Increased exposure to thiotepa.



[PMID 24465030OA-icon.png] GSTP1 and TNF Gene Variants and Associations between Air Pollution and Incident Childhood Asthma: The Traffic, Asthma and Genetics (TAG) Study


[PMID 24610081] Associations Between SNPs Within Antioxidant Genes and the Risk of Prostate Cancer in the Siberian Region of Russia


[PMID 22487578] Association of glutathione S-transferase pi isoform single-nucleotide polymorphisms with exudative age-related macular degeneration in a Chinese population.


[PMID 22868256OA-icon.png] A prospective validation pharmacogenomic study in the adjuvant setting of colorectal cancer patients treated with the 5-fluorouracil/leucovorin/oxaliplatin (FOLFOX4) regimen.


[PMID 23175176OA-icon.png] Variation in PAH-related DNA adduct levels among non-smokers: the role of multiple genetic polymorphisms and nucleotide excision repair phenotype.


[PMID 23179585] Possible contribution of GSTP1 and other xenobiotic metabolizing genes to vitiligo susceptibility.


[PMID 23663310OA-icon.png] Investigating highly replicated asthma genes as candidate genes for allergic rhinitis.


[PMID 25383449] Docetaxel-induced neuropathy: A pharmacogenetic case-control study of 150 women with early-stage breast cancer


[PMID 27729156] Analysis of genetic and non genetic risk factors for cisplatin ototoxicity in pediatric patients.