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rs1143684

From SNPedia

Orientationplus
Stabilizedplus
Make rs1143684(C;C)
Make rs1143684(C;T)
Make rs1143684(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position3010156
GeneNQO2
is asnp
is mentioned by
dbSNPrs1143684
ebirs1143684
HLIrs1143684
Exacrs1143684
Varsomers1143684
Maprs1143684
PheGenIrs1143684
hapmaprs1143684
1000 genomesrs1143684
hgdprs1143684
ensemblrs1143684
gopubmedrs1143684
geneviewrs1143684
scholarrs1143684
googlers1143684
pharmgkbrs1143684
gwascentralrs1143684
openSNPrs1143684
23andMers1143684
23andMe allrs1143684
SNP Nexus

SNPshotrs1143684
SNPdbers1143684
MSV3drs1143684
GWAS Ctlgrs1143684
GMAF0.1979
Max Magnitude
? (C;C) (C;T) (T;T) 28

[PMID 21351093] Association of superoxide dismutases and NAD(P)H quinone oxidoreductases with prognosis of patients with breast carcinomas


[PMID 18538895] Investigation of a functional quinine oxidoreductase (NQO2) polymorphism and cognitive decline.


[PMID 18698231OA-icon.png] Polymorphisms affecting gene transcription and mRNA processing in pharmacogenetic candidate genes: detection through allelic expression imbalance in human target tissues.


[PMID 20966810] Superoxide dismutase and nicotinamide adenine dinucleotide phosphate: quinone oxidoreductase polymorphisms and pancreatic cancer risk.


[PMID 21946896] Two minor NQO1 and NQO2 alleles predict poor response of breast cancer patients to adjuvant doxorubicin and cyclophosphamide therapy.


GET Evidence
NQO2-L47F
aa_change Leu47Phe
aa_change_short L47F
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.845138
summary



[PMID 24631540OA-icon.png] The two common polymorphic forms of human NRH-quinone oxidoreductase 2 (NQO2) have different biochemical properties