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rs1154404

From SNPedia

Orientationminus
Stabilizedminus
Make rs1154404(A;A)
Make rs1154404(A;T)
Make rs1154404(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position99087853
GeneADH5, SLC3A1
is asnp
is mentioned by
dbSNPrs1154404
ebirs1154404
HLIrs1154404
Exacrs1154404
Varsomers1154404
Maprs1154404
PheGenIrs1154404
hapmaprs1154404
1000 genomesrs1154404
hgdprs1154404
ensemblrs1154404
gopubmedrs1154404
geneviewrs1154404
scholarrs1154404
googlers1154404
pharmgkbrs1154404
gwascentralrs1154404
openSNPrs1154404
23andMers1154404
23andMe allrs1154404
SNP Nexus

SNPshotrs1154404
SNPdbers1154404
MSV3drs1154404
GWAS Ctlgrs1154404
GMAF0.2612
Max Magnitude
? (A;A) (A;T) (T;T) 28
linked to asthma

[PMID 17543375OA-icon.png] Carrying 1 or 2 copies of the minor allele of SNP rs1154404 was associated with decreased risk of asthma (relative risk [RR], 0.77; 95% CI, 0.61-0.97; P = .028 for 1 copy and RR, 0.66; 95% CI, 0.44-0.99; P = .046 for 2 copies). Homozygosity for the minor allele increased risk of asthma (RR, 1.60; 95% CI, 1.13-2.26; P = .0077).

CLINICAL IMPLICATIONS: The association of GSNOR polymorphisms with asthma suggests a potential therapeutic target.