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rs11635424

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 2 <0.70x risk for restless legs
(A;G) 1.5 0.70x risk for restless legs
(G;G) 1 normal risk of restless leg syndrome
ReferenceGRCh38 38.1/141
Chromosome15
Position67745240
GeneMAP2K5
is asnp
is mentioned by
dbSNPrs11635424
ebirs11635424
HLIrs11635424
Exacrs11635424
Varsomers11635424
Maprs11635424
PheGenIrs11635424
hapmaprs11635424
1000 genomesrs11635424
hgdprs11635424
ensemblrs11635424
gopubmedrs11635424
geneviewrs11635424
scholarrs11635424
googlers11635424
pharmgkbrs11635424
gwascentralrs11635424
openSNPrs11635424
23andMers11635424
23andMe allrs11635424
SNP Nexus

SNPshotrs11635424
SNPdbers11635424
MSV3drs11635424
GWAS Ctlgrs11635424
GMAF0.4545
Max Magnitude2
? (A;A) (A;G) (G;G) 28
rs11635424, a SNP located in a region of chromosome 15q, has been linked to a lower frequency of restless legs syndrome, a common sleep disorder, with an overall odds ratio of 0.70 (CI: 0.59-0.82) for the (A) minor allele. [PMID 17637780]
Neighborrs12593813
Distance726
[PMID 19279021OA-icon.png] Replication of restless legs syndrome loci in three European populations.


GET Evidence
rs11635424
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.398438
summary