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rs11655505

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs11655505(A;A)
Make rs11655505(A;G)
ReferenceGRCh38 38.1/141
Chromosome17
Position43126360
GeneBRCA1
is asnp
is mentioned by
dbSNPrs11655505
ebirs11655505
HLIrs11655505
Exacrs11655505
Varsomers11655505
Maprs11655505
PheGenIrs11655505
hapmaprs11655505
1000 genomesrs11655505
hgdprs11655505
ensemblrs11655505
gopubmedrs11655505
geneviewrs11655505
scholarrs11655505
googlers11655505
pharmgkbrs11655505
gwascentralrs11655505
openSNPrs11655505
23andMers11655505
23andMe allrs11655505
SNP Nexus

SNPshotrs11655505
SNPdbers11655505
MSV3drs11655505
GWAS Ctlgrs11655505
GMAF0.3274
Max Magnitude0
Although BRCA1 gene SNP rs11655505(T) is mentioned in PharmGKB as having a protective association with risk for breast cancer, a more recent study of 2912 female breast cancer cases and 2783 unaffected female controls from four Caucasian breast cancer studies found no evidence for any association between rs11655505 and breast cancer risk.[PMID 20413709]



GET Evidence
rs11655505
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.304688
summary



[PMID 23263908] Association of BRCA1 promoter methylation with rs11655505 (c.2265C>T) variants and decreased gene expression in sporadic breast cancer.


ClinVar
Risk rs11655505(A;A)
Alt rs11655505(A;A)
Reference rs11655505(G;G)
Significance Non-pathogenic
Disease Breast-ovarian cancer
Variation info
Gene NBR2 BRCA1
CLNDBN Breast-ovarian cancer, familial 1
Reversed 0
HGVS NC_000017.10:g.41278377G>A
CLNSRC
CLNACC RCV000191529.1,