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rs1172822

From SNPedia

Orientationplus
Stabilizedplus
Make rs1172822(C;C)
Make rs1172822(C;T)
Make rs1172822(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position55308477
GeneBRSK1
is asnp
is mentioned by
dbSNPrs1172822
ebirs1172822
HLIrs1172822
Exacrs1172822
Varsomers1172822
Maprs1172822
PheGenIrs1172822
hapmaprs1172822
1000 genomesrs1172822
hgdprs1172822
ensemblrs1172822
gopubmedrs1172822
geneviewrs1172822
scholarrs1172822
googlers1172822
pharmgkbrs1172822
gwascentralrs1172822
openSNPrs1172822
23andMers1172822
23andMe allrs1172822
SNP Nexus

SNPshotrs1172822
SNPdbers1172822
MSV3drs1172822
GWAS Ctlgrs1172822
GMAF0.2691
Max Magnitude
? (C;C) (C;T) (T;T) 28

23andMe blog rs1172822(T) Menopause about 25 weeks earlier

GWAS snp
PMID [PMID 19448619OA-icon.png]
Trait Menopause
Title Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
Risk Allele T
P-val 6E-11
Odds Ratio 0.39 [0.27-0.51] years younger
GWAS snp
PMID [PMID 19448621OA-icon.png]
Trait Menarche and menopause (age at onset)
Title Genome-wide association studies identify loci associated with age at menarche and age at natural menopause
Risk Allele T
P-val 2E-19
Odds Ratio 0.49 [0.38-0.60] years younger
OMIM612884
Desc
Variant
Relatedalso
[PMID 19664201OA-icon.png] Genetic and genomic insights into age at natural menopause.


GET Evidence
rs1172822
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.234375
summary



[PMID 23508249OA-icon.png] Replication of genetic loci for ages at menarche and menopause in the multi-ethnic Population Architecture using Genomics and Epidemiology (PAGE) study


[PMID 23536822OA-icon.png] Evaluating GWAS-Identified SNPs for Age at Natural Menopause among Chinese Women


[PMID 23592221] Shared genetic factors for age at natural menopause in Iranian and European women


[PMID 23360674] Genetic variation may modify ovarian reserve in female childhood cancer survivors.