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rs11754661

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 0 common on affy axiom data
Make rs11754661(A;A)
Make rs11754661(A;G)
ReferenceGRCh38 38.1/141
Chromosome6
Position150885942
GeneMTHFD1L
is asnp
is mentioned by
dbSNPrs11754661
ebirs11754661
HLIrs11754661
Exacrs11754661
Varsomers11754661
Maprs11754661
PheGenIrs11754661
hapmaprs11754661
1000 genomesrs11754661
hgdprs11754661
ensemblrs11754661
gopubmedrs11754661
geneviewrs11754661
scholarrs11754661
googlers11754661
pharmgkbrs11754661
gwascentralrs11754661
openSNPrs11754661
23andMers11754661
23andMe allrs11754661
SNP Nexus

SNPshotrs11754661
SNPdbers11754661
MSV3drs11754661
GWAS Ctlgrs11754661
GMAF0.03811
Max Magnitude0
? (A;A) (A;G) (G;G) 28

This SNP in the MTHFD1L gene is associated with late-onset Alzheimer's disease, according to an article in PLoS Genetics.

[PMID 20885792OA-icon.png] Dementia revealed: novel chromosome 6 locus for late-onset Alzheimer disease provides genetic evidence for folate-pathway abnormalities


[PMID 21383495] The MTHFD1L Gene rs11754661 Marker is Not Associated with Alzheimer's Disease in a Sample of the Spanish Population


[PMID 21741665] The MTHFD1L gene rs11754661 marker is associated with susceptibility to Alzheimer's disease in the Chinese Han population


[PMID 22330827] Replication of the MTHFD1L gene association with late-onset Alzheimer's disease in a Northern Han Chinese population.


GET Evidence
rs11754661
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0625
summary