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rs1176744

From SNPedia

Orientationminus
Stabilizedminus
Make rs1176744(G;G)
Make rs1176744(G;T)
Make rs1176744(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position113932306
GeneHTR3B
is asnp
is mentioned by
dbSNPrs1176744
ebirs1176744
HLIrs1176744
Exacrs1176744
Varsomers1176744
Maprs1176744
PheGenIrs1176744
hapmaprs1176744
1000 genomesrs1176744
hgdprs1176744
ensemblrs1176744
gopubmedrs1176744
geneviewrs1176744
scholarrs1176744
googlers1176744
pharmgkbrs1176744
gwascentralrs1176744
openSNPrs1176744
23andMers1176744
23andMe allrs1176744
SNP Nexus

SNPshotrs1176744
SNPdbers1176744
MSV3drs1176744
GWAS Ctlgrs1176744
GMAF0.343
Max Magnitude
? (G;G) (G;T) (T;T) 28
OMIM604654
Desc5-@HYDROXYTRYPTAMINE RECEPTOR 3B; HTR3B
Variant
Relatedalso


[PMID 19741568] Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders


[PMID 20838391OA-icon.png] Functional genetic variants that increase synaptic serotonin and 5-HT3 receptor sensitivity predict alcohol and drug dependence


[PMID 21570824] Clinical and genetic factors associated with nausea and vomiting in cancer patients receiving opioids

[PMID 17708757OA-icon.png] Genome bioinformatic analysis of nonsynonymous SNPs.

[PMID 18330705OA-icon.png] Physiogenomic analysis of localized FMRI brain activity in schizophrenia.

[PMID 19185213OA-icon.png] HTR3B is associated with alcoholism with antisocial behavior and alpha EEG power--an intermediate phenotype for alcoholism and co-morbid behaviors.

[PMID 21172166OA-icon.png] Pharmacogenetics of antidepressant response.

[PMID 21184810] Are serotonin 3A and 3B receptor genes associated with suicidal behavior in schizophrenia subjects?


GET Evidence
HTR3B-Y129S
aa_change Tyr129Ser
aa_change_short Y129S
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.357103
summary



[PMID 23757001OA-icon.png] Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence


[PMID 23290502OA-icon.png] Serotonin transporter and receptor genes significantly impact nicotine dependence through genetic interactions in both European American and African American smokers