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rs11881222

From SNPedia

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Stabilizedplus
Make rs11881222(A;A)
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Make rs11881222(G;G)
ReferenceGRCh38 38.1/141
Chromosome19
Position39244283
GeneIFNL3
is asnp
is mentioned by
dbSNPrs11881222
ebirs11881222
HLIrs11881222
Exacrs11881222
Varsomers11881222
Maprs11881222
PheGenIrs11881222
hapmaprs11881222
1000 genomesrs11881222
hgdprs11881222
ensemblrs11881222
gopubmedrs11881222
geneviewrs11881222
scholarrs11881222
googlers11881222
pharmgkbrs11881222
gwascentralrs11881222
openSNPrs11881222
23andMers11881222
23andMe allrs11881222
SNP Nexus

SNPshotrs11881222
SNPdbers11881222
MSV3drs11881222
GWAS Ctlgrs11881222
GMAF0.2576
Max Magnitude
? (A;A) (A;G) (G;G) 28

[PMID 19749757] Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis C


[PMID 21070502] Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort


[PMID 20887330] High sensitivity assay using serum sample for IL28B genotyping to predict treatment response in chronic hepatitis C patients.


[PMID 21389156OA-icon.png] The rs8099917 polymorphism, when determined by a suitable genotyping method, is a better predictor for response to pegylated alpha interferon/ribavirin therapy in Japanese patients than other single nucleotide polymorphisms associated with interleukin-28B.


GET Evidence
rs11881222
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.3125
summary



[PMID 23866096] The predictive value of IL28B rs12979860, rs11881222 and rs8099917 polymorphisms and IP-10 in the therapeutic response of Egyptian genotype 4 patients


[PMID 24621321OA-icon.png] Severe thrombocytopenia in a patient with inosine triphosphatase (ITPA)-CC genotype caused by pegylated interferon (IFN)-alpha-2a with ribavirin therapy: a case report


[PMID 23103287] IL28B polymorphisms are associated with severity of liver disease in human immunodeficiency virus (HIV) patients coinfected with hepatitis C virus.


[PMID 23135173] Analysis of IL28B alleles with virologic response patterns and plasma cytokine levels in HIV/HCV-coinfected patients.