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rs12129861

From SNPedia

Orientationminus
Stabilizedplus
Make rs12129861(A;A)
Make rs12129861(A;G)
Make rs12129861(G;G)
ReferenceGRCh38 38.1/141
Chromosome1
Position145709377
GenePDZK1
is asnp
is mentioned by
dbSNPrs12129861
ebirs12129861
HLIrs12129861
Exacrs12129861
Varsomers12129861
Maprs12129861
PheGenIrs12129861
hapmaprs12129861
1000 genomesrs12129861
hgdprs12129861
ensemblrs12129861
gopubmedrs12129861
geneviewrs12129861
scholarrs12129861
googlers12129861
pharmgkbrs12129861
gwascentralrs12129861
openSNPrs12129861
23andMers12129861
23andMe allrs12129861
SNP Nexus

SNPshotrs12129861
SNPdbers12129861
MSV3drs12129861
GWAS Ctlgrs12129861
GMAF0.3494
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19503597OA-icon.png]
Trait Uric acid concentrations
Title Meta-Analysis of 28,141 Individuals Identifies Common Variants within Five New Loci That Influence Uric Acid Concentrations
Risk Allele A
P-val 3E-9
Odds Ratio 0.06 [0.042-0.083] mg/dl decrease


[PMID 19890391OA-icon.png] Common polymorphisms influencing serum uric Acid levels contribute to susceptibility to gout, but not to coronary artery disease


[PMID 19861489] Replication of the five novel loci for uric acid concentrations and potential mediating mechanisms.


GET Evidence
rs12129861
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.31746
summary



[PMID 23712608] Genetic variability related to serum uric acid concentration and risk of Parkinson's disease.


[PMID 26290326] Polymorphisms in GCKR, SLC17A1 and SLC22A12 were associated with phenotype gout in Han Chinese males: a case-control study