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rs12185268

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 common on affy axiom data
Make rs12185268(A;G)
Make rs12185268(G;G)
ReferenceGRCh38 38.1/141
Chromosome17
Position45846317
GeneMAPT-AS1, SPPL2C
is asnp
is mentioned by
dbSNPrs12185268
ebirs12185268
HLIrs12185268
Exacrs12185268
Varsomers12185268
Maprs12185268
PheGenIrs12185268
hapmaprs12185268
1000 genomesrs12185268
hgdprs12185268
ensemblrs12185268
gopubmedrs12185268
geneviewrs12185268
scholarrs12185268
googlers12185268
pharmgkbrs12185268
gwascentralrs12185268
openSNPrs12185268
23andMers12185268
23andMe allrs12185268
SNP Nexus

SNPshotrs12185268
SNPdbers12185268
MSV3drs12185268
GWAS Ctlgrs12185268
GMAF0.1162
Max Magnitude0
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 21738487OA-icon.png]
Trait
Title Web-based genome-wide association study identifies two novel Loci and a substantial genetic component for Parkinson's disease.
Risk Allele A
P-val 3E-14
Odds Ratio 1.3000 [1.22-1.39]


[PMID 18985386OA-icon.png] Genomewide association study for susceptibility genes contributing to familial Parkinson disease.


[PMID 20070850OA-icon.png] Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.


GET Evidence
NM_175882-I471V
aa_change Ile471Val
aa_change_short I471V
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.0901639
summary



[PMID 25929833] Parkinson's Disease Genetic Loci in Rapid Eye Movement Sleep Behavior Disorder