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rs12188950

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs12188950(C;T)
Make rs12188950(T;T)
ReferenceGRCh38 38.1/141
Chromosome5
Position60487490
GenePDE4D
is asnp
is mentioned by
dbSNPrs12188950
ebirs12188950
HLIrs12188950
Exacrs12188950
Varsomers12188950
Maprs12188950
PheGenIrs12188950
hapmaprs12188950
1000 genomesrs12188950
hgdprs12188950
ensemblrs12188950
gopubmedrs12188950
geneviewrs12188950
scholarrs12188950
googlers12188950
pharmgkbrs12188950
gwascentralrs12188950
openSNPrs12188950
23andMers12188950
23andMe allrs12188950
SNP Nexus

SNPshotrs12188950
SNPdbers12188950
MSV3drs12188950
GWAS Ctlgrs12188950
GMAF0.09229
Max Magnitude0
In both a multi-site study including 2,500+ Swedish patients and a meta-analysis of 10,000+ patients in 17 publications, no association between rs12188950 and risk for ischemic stroke was found.

[PMID 22274584OA-icon.png]

? (C;C) (C;T) (T;T) 28
[PMID 16835261OA-icon.png] Phosphodiesterase 4D polymorphisms and the risk of cerebral infarction in a biracial population: the Stroke Prevention in Young Women Study.


[PMID 18398440] Ischaemic stroke in hypertensive patients is associated with variations in the PDE4D genome region.


[PMID 19409523OA-icon.png] Multilocus Bayesian meta-analysis of gene-disease associations.


[PMID 19426955OA-icon.png] Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.


[PMID 20540798OA-icon.png] Sex-differential genetic effect of phosphodiesterase 4D (PDE4D) on carotid atherosclerosis.