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rs121908260

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(G;G) 0 common in clinvar
Make rs121908260(A;A)
Make rs121908260(A;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position2160835
GeneINS, INS-IGF2
is asnp
is mentioned by
dbSNPrs121908260
ebirs121908260
HLIrs121908260
Exacrs121908260
Varsomers121908260
Maprs121908260
PheGenIrs121908260
hapmaprs121908260
1000 genomesrs121908260
hgdprs121908260
ensemblrs121908260
gopubmedrs121908260
geneviewrs121908260
scholarrs121908260
googlers121908260
pharmgkbrs121908260
gwascentralrs121908260
openSNPrs121908260
23andMers121908260
23andMe allrs121908260
SNP Nexus

SNPshotrs121908260
SNPdbers121908260
MSV3drs121908260
GWAS Ctlgrs121908260
Max Magnitude0
OMIM176730
Desc
Variant0015
Relatedalso
ClinVar
Risk rs121908260(A;A)
Alt rs121908260(A;A)
Reference rs121908260(G;G)
Significance Pathogenic
Disease Maturity-onset diabetes of the young
Variation info
Gene INS INS-IGF2
CLNDBN Maturity-onset diabetes of the young, type 10
Reversed 1
HGVS NC_000011.9:g.2182065C>T
CLNSRC OMIM Allelic Variant UniProtKB (variants)
CLNACC RCV000014323.27,


[PMID 18192540] Mutations in the insulin gene can cause MODY and autoantibody-negative type 1 diabetes.


[PMID 20226046OA-icon.png] Further evidence that mutations in INS can be a rare cause of Maturity-Onset Diabetes of the Young (MODY).