Have questions? Visit https://www.reddit.com/r/SNPedia

rs12191877

From SNPedia

Orientationplus
Stabilizedplus
Make rs12191877(C;C)
Make rs12191877(C;T)
Make rs12191877(T;T)
ReferenceGRCh38 38.1/141
Chromosome6
Position31285148
is asnp
is mentioned by
dbSNPrs12191877
ebirs12191877
HLIrs12191877
Exacrs12191877
Varsomers12191877
Maprs12191877
PheGenIrs12191877
hapmaprs12191877
1000 genomesrs12191877
hgdprs12191877
ensemblrs12191877
gopubmedrs12191877
geneviewrs12191877
scholarrs12191877
googlers12191877
pharmgkbrs12191877
gwascentralrs12191877
openSNPrs12191877
23andMers12191877
23andMe allrs12191877
SNP Nexus

SNPshotrs12191877
SNPdbers12191877
MSV3drs12191877
GWAS Ctlgrs12191877
GMAF0.107
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19169254OA-icon.png]
Trait Psoriasis
Title Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
Risk Allele T
P-val 1E-100
Odds Ratio 2.64 None


[PMID 19680446OA-icon.png] Multiple Loci within the major histocompatibility complex confer risk of psoriasis


GWAS snp
PMID [PMID 20953188OA-icon.png]
Trait
Title Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
Risk Allele
P-val 4E-32
Odds Ratio 2.7900 [2.35-3.33] (Panel A)

[PMID 19262574OA-icon.png] Genome-wide association scan yields new insights into the immunopathogenesis of psoriasis.

[PMID 20606885OA-icon.png] Genetics of psoriasis and psoriatic arthritis.

[PMID 21214922OA-icon.png] Psoriasis prediction from genome-wide SNP profiles.

[PMID 21304891OA-icon.png] A study of CNVs as trait-associated polymorphisms and as expression quantitative trait loci.


GET Evidence
rs12191877
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.101562
summary



[PMID 24566688] Deletion of late cornified envelope genes, LCE3C_LCE3B-del, is not associated with psoriatic arthritis in Tunisian patients


[PMID 24566686] Human leukocyte antigen (HLA)-C polymorphisms are associated with a decreased risk of rheumatoid arthritis