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rs12251307

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs12251307(C;T)
Make rs12251307(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position6081532
is asnp
is mentioned by
dbSNPrs12251307
ebirs12251307
HLIrs12251307
Exacrs12251307
Varsomers12251307
Maprs12251307
PheGenIrs12251307
hapmaprs12251307
1000 genomesrs12251307
hgdprs12251307
ensemblrs12251307
gopubmedrs12251307
geneviewrs12251307
scholarrs12251307
googlers12251307
pharmgkbrs12251307
gwascentralrs12251307
openSNPrs12251307
23andMers12251307
23andMe allrs12251307
SNP Nexus

SNPshotrs12251307
SNPdbers12251307
MSV3drs12251307
GWAS Ctlgrs12251307
GMAF0.1919
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18978792OA-icon.png]
Trait Type 1 diabetes
Title Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
Risk Allele T
P-val 0.000002
Odds Ratio NR NR
GWAS snp
PMID [PMID 19430480OA-icon.png]
Trait Type 1 diabetes
Title Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
Risk Allele
P-val 1E-13
Odds Ratio NR NR



[PMID 19956099OA-icon.png] The type I diabetes association of the IL2RA locus

[PMID 17554260OA-icon.png] Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetes.

[PMID 19265545OA-icon.png] Contrasting genetic association of IL2RA with SLE and ANCA-associated vasculitis.

[PMID 19468064OA-icon.png] Parasites represent a major selective force for interleukin genes and shape the genetic predisposition to autoimmune conditions.

[PMID 19956101OA-icon.png] Overview of the Rapid Response data.

[PMID 19956106OA-icon.png] Analysis of 19 genes for association with type I diabetes in the Type I Diabetes Genetics Consortium families.


GET Evidence
rs12251307
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.164062
summary