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rs12286037

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0
Make rs12286037(C;T)
Make rs12286037(T;T)
ReferenceGRCh38 38.1/141
Chromosome11
Position116781491
GeneZPR1
is asnp
is mentioned by
dbSNPrs12286037
ebirs12286037
HLIrs12286037
Exacrs12286037
Varsomers12286037
Maprs12286037
PheGenIrs12286037
hapmaprs12286037
1000 genomesrs12286037
hgdprs12286037
ensemblrs12286037
gopubmedrs12286037
geneviewrs12286037
scholarrs12286037
googlers12286037
pharmgkbrs12286037
gwascentralrs12286037
openSNPrs12286037
23andMers12286037
23andMe allrs12286037
SNP Nexus

SNPshotrs12286037
SNPdbers12286037
MSV3drs12286037
GWAS Ctlgrs12286037
GMAF0.08861
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18193043]
Trait Triglycerides
Title Newly identified loci that influence lipid concentrations and risk of coronary artery disease
Risk Allele T
P-val 1E-26
Odds Ratio 25.82 [NR] mg/dl higher
GWAS snp
PMID [PMID 20442857OA-icon.png]
Trait Lipoprotein-associated phospholipase A2 activity and mass
Title Genome-wide association study of Lp-PLA(2) activity and mass in the Framingham Heart Study
Risk Allele T
P-val 4E-8
Odds Ratio 6.40 [NR] nmol/ml/min increase
GWAS snp
PMID [PMID 21386085OA-icon.png]
Trait
Title A Bivariate Genome-Wide Approach to Metabolic Syndrome: STAMPEED Consortium
Risk Allele C
P-val 1E-8
Odds Ratio 0.3200 [0.20-0.44] unit decrease


[PMID 18852197OA-icon.png] Metabolic and cardiovascular traits: an abundance of recently identified common genetic variants.


[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.


[PMID 19656773OA-icon.png] A polygenic basis for four classical Fredrickson hyperlipoproteinemia phenotypes that are characterized by hypertriglyceridemia.


GET Evidence
rs12286037
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.101562
summary



[PMID 26244076OA-icon.png] The interaction of Apolipoprotein A5 gene promoter region T-1131C polymorphism (rs12286037) and lifestyle modification on plasma triglyceride levels in Japanese