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rs12316150

From SNPedia

Orientationplus
Stabilizedplus
Make rs12316150(A;A)
Make rs12316150(A;T)
Make rs12316150(T;T)
ReferenceGRCh38 38.1/141
Chromosome12
Position10159692
GeneOLR1
is asnp
is mentioned by
dbSNPrs12316150
ebirs12316150
HLIrs12316150
Exacrs12316150
Varsomers12316150
Maprs12316150
PheGenIrs12316150
hapmaprs12316150
1000 genomesrs12316150
hgdprs12316150
ensemblrs12316150
gopubmedrs12316150
geneviewrs12316150
scholarrs12316150
googlers12316150
pharmgkbrs12316150
gwascentralrs12316150
openSNPrs12316150
23andMers12316150
23andMe allrs12316150
SNP Nexus

SNPshotrs12316150
SNPdbers12316150
MSV3drs12316150
GWAS Ctlgrs12316150
GMAF0.04821
Max Magnitude
? (A;A) (A;T) (T;T) 28
rs12316150, a SNP also known as +1071, is located in the 3' untranslated region of the oxidized low density lipoprotein (lectin-like) receptor 1 OLR1 gene, which is also known as the LOX-1 gene.

The rs12316150 risk allele has been associated with increased risk for Alzheimer's disease in several studies of ~200 Southern Italian Alzheimer patients, but only within the context of a haplotype including one or both of neighboring SNPs rs1050283 and rs669.[PMID 15860461, PMID 18191876]

Neighborrs1050283
Distance2


ClinVar
Risk rs12316150(T;T)
Alt rs12316150(T;T)
Reference rs12316150(A;A)
Significance Other
Disease Myocardial infarction
Variation info
Gene OLR1
CLNDBN Myocardial infarction
Reversed 0
HGVS NC_000012.11:g.10312291A\x3d
CLNSRC OMIM Allelic Variant
CLNACC RCV000007410.4,