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rs12498742

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 1.5 1.25 increased risk for gout
(G;G) 0 normal reduced risk of gout
Make rs12498742(A;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position9942428
GeneSLC2A9
is asnp
is mentioned by
dbSNPrs12498742
ebirs12498742
HLIrs12498742
Exacrs12498742
Varsomers12498742
Maprs12498742
PheGenIrs12498742
hapmaprs12498742
1000 genomesrs12498742
hgdprs12498742
ensemblrs12498742
gopubmedrs12498742
geneviewrs12498742
scholarrs12498742
googlers12498742
pharmgkbrs12498742
gwascentralrs12498742
openSNPrs12498742
23andMers12498742
23andMe allrs12498742
SNP Nexus

SNPshotrs12498742
SNPdbers12498742
MSV3drs12498742
GWAS Ctlgrs12498742
GMAF0.2553
Max Magnitude1.5
[PMID 23263486OA-icon.png] Each copy of the minor (G) allele appears to confer reduced risk for gout based on combined data from over 140,000 individuals of European ancestry within the Global Urate Genetics Consortium (GUGC), replicating an association reported earlier for a linked SNP in this gene.
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 23263486OA-icon.png]
Trait Urate levels
Title Genome-wide association analyses identify 18 new loci associated with serum urate concentrations.
Risk Allele A
P-val 1E-700
Odds Ratio .37 [0.36-0.38] mg/dl increase


[PMID 19503597OA-icon.png] Meta-analysis of 28,141 individuals identifies common variants within five new loci that influence uric acid concentrations.