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rs1250550

From SNPedia

Orientationminus
Stabilizedminus
Make rs1250550(G;G)
Make rs1250550(G;T)
Make rs1250550(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position79300560
GeneZMIZ1
is asnp
is mentioned by
dbSNPrs1250550
ebirs1250550
HLIrs1250550
Exacrs1250550
Varsomers1250550
Maprs1250550
PheGenIrs1250550
hapmaprs1250550
1000 genomesrs1250550
hgdprs1250550
ensemblrs1250550
gopubmedrs1250550
geneviewrs1250550
scholarrs1250550
googlers1250550
pharmgkbrs1250550
gwascentralrs1250550
openSNPrs1250550
23andMers1250550
23andMe allrs1250550
SNP Nexus

SNPshotrs1250550
SNPdbers1250550
MSV3drs1250550
GWAS Ctlgrs1250550
GMAF0.2952
Max Magnitude
? (G;G) (G;T) (T;T) 28
GWAS snp
PMID [PMID 19915574OA-icon.png]
Trait Inflammatory bowel disease (early onset)
Title Common variants at five new loci associated with early-onset inflammatory bowel disease
Risk Allele
P-val 6E-9
Odds Ratio 1.16 [1.09-1.25]


[PMID 20473688] Association between genome-wide association studies reported SNPs and pediatric-onset Crohn's disease in Canadian children

GWAS snp
PMID [PMID 21102463OA-icon.png]
Trait
Title Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci
Risk Allele G
P-val 1E-30
Odds Ratio 1.1900 [1.15-1.23]


[PMID 17068223OA-icon.png] A genome-wide association study identifies IL23R as an inflammatory bowel disease gene.


GET Evidence
rs1250550
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.25
summary



GWAS snp
PMID [PMID 21833088OA-icon.png]
Trait Multiple sclerosis
Title Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.
Risk Allele A
P-val 6E-9
Odds Ratio 1.10 [1.09-1.12]


[PMID 23543094OA-icon.png] Testing for associations between loci and environmental gradients using latent factor mixed models.