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rs12623467

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs12623467(C;T)
Make rs12623467(T;T)
ReferenceGRCh38 38.1/141
Chromosome2
Position50997951
GeneNRXN1
is asnp
is mentioned by
dbSNPrs12623467
ebirs12623467
HLIrs12623467
Exacrs12623467
Varsomers12623467
Maprs12623467
PheGenIrs12623467
hapmaprs12623467
1000 genomesrs12623467
hgdprs12623467
ensemblrs12623467
gopubmedrs12623467
geneviewrs12623467
scholarrs12623467
googlers12623467
pharmgkbrs12623467
gwascentralrs12623467
openSNPrs12623467
23andMers12623467
23andMe allrs12623467
SNP Nexus

SNPshotrs12623467
SNPdbers12623467
MSV3drs12623467
GWAS Ctlgrs12623467
GMAF0.2103
Max Magnitude0
? (C;C) (C;T) (T;T) 28
rs12623467 increases susceptibility to Substance dependence, Nicotine 2.09 times for carriers of the C allele [PMID 17158188OA-icon.png]


[PMID 18270208OA-icon.png] Significant association of the neurexin-1 gene (NRXN1) with nicotine dependence in European- and African-American smokers.


[PMID 18565990OA-icon.png] Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.


[PMID 18783506OA-icon.png] Association of a single nucleotide polymorphism in neuronal acetylcholine receptor subunit alpha 5 (CHRNA5) with smoking status and with 'pleasurable buzz' during early experimentation with smoking.