Have questions? Visit https://www.reddit.com/r/SNPedia

rs12676

From SNPedia

Orientationminus
Stabilizedminus
Make rs12676(G;G)
Make rs12676(G;T)
Make rs12676(T;T)
ReferenceGRCh38 38.1/141
Chromosome3
Position53823776
GeneCHDH
is asnp
is mentioned by
dbSNPrs12676
ebirs12676
HLIrs12676
Exacrs12676
Varsomers12676
Maprs12676
PheGenIrs12676
hapmaprs12676
1000 genomesrs12676
hgdprs12676
ensemblrs12676
gopubmedrs12676
geneviewrs12676
scholarrs12676
googlers12676
pharmgkbrs12676
gwascentralrs12676
openSNPrs12676
23andMers12676
23andMe allrs12676
SNP Nexus

SNPshotrs12676
SNPdbers12676
MSV3drs12676
GWAS Ctlgrs12676
GMAF0.1607
Max Magnitude

[PMID 22558321OA-icon.png] Choline Dehydrogenase Polymorphism rs12676 Is a Functional Variation and Is Associated with Changes in Human Sperm Cell Function [PMID 16816108OA-icon.png] Common genetic polymorphisms affect the human requirement for the nutrient choline.


[PMID 17613168OA-icon.png] Gene response elements, genetic polymorphisms and epigenetics influence the human dietary requirement for choline.


[PMID 17616785OA-icon.png] Lymphocyte gene expression in subjects fed a low-choline diet differs between those who develop organ dysfunction and those who do not.


[PMID 18230680OA-icon.png] Choline metabolism and risk of breast cancer in a population-based study.


[PMID 18789905OA-icon.png] Genetic polymorphisms in methyl-group metabolism and epigenetics: lessons from humans and mouse models.


[PMID 19116320OA-icon.png] Importance of methyl donors during reproduction.


[PMID 19261726OA-icon.png] Epigenetic mechanisms for nutrition determinants of later health outcomes.

GET Evidence
CHDH-L78R
aa_change Leu78Arg
aa_change_short L78R
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.776821
summary



[PMID 25921832] Evidence for negative selection of gene variants that increase dependence on dietary choline in a Gambian cohort