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rs12720270

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs12720270(C;T)
Make rs12720270(T;T)
ReferenceGRCh38 38.1/141
Chromosome19
Position10365084
GeneTYK2
is asnp
is mentioned by
dbSNPrs12720270
ebirs12720270
HLIrs12720270
Exacrs12720270
Varsomers12720270
Maprs12720270
PheGenIrs12720270
hapmaprs12720270
1000 genomesrs12720270
hgdprs12720270
ensemblrs12720270
gopubmedrs12720270
geneviewrs12720270
scholarrs12720270
googlers12720270
pharmgkbrs12720270
gwascentralrs12720270
openSNPrs12720270
23andMers12720270
23andMe allrs12720270
SNP Nexus

SNPshotrs12720270
SNPdbers12720270
MSV3drs12720270
GWAS Ctlgrs12720270
GMAF0.2181
Max Magnitude0

[PMID 19440814] Lack of association between tyrosine kinase 2 (TYK2) gene polymorphisms and susceptibility to SLE in a Japanese population; No association was seen between this SNP and SLE in a study of 411 Japanese SLE patients.


[PMID 21140222] Meta-analysis of TYK2 gene polymorphisms association with susceptibility to autoimmune and inflammatory diseases [PMID 15657875OA-icon.png] Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.

[PMID 19442287OA-icon.png] Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study.

[PMID 19567624] Evidence for genetic association and interaction between the TYK2 and IRF5 genes in systemic lupus erythematosus.


[PMID 22592861] Associations between PXK and TYK2 polymorphisms and systemic lupus erythematosus: a meta-analysis.


[PMID 23000200] TYK2 rs34536443 polymorphism is associated with a decreased susceptibility to endometriosis-related infertility.


[PMID 26294277] Genetic association and interaction between the IRF5 and TYK2 genes and systemic lupus erythematosus in the Han Chinese population