Have questions? Visit https://www.reddit.com/r/SNPedia

rs12772169

From SNPedia

Orientationplus
Stabilizedplus
Make rs12772169(C;C)
Make rs12772169(C;T)
Make rs12772169(T;T)
ReferenceGRCh38 38.1/142
Chromosome10
Position94645572
GeneLOC100130970
is asnp
is mentioned by
dbSNPrs12772169
ebirs12772169
HLIrs12772169
Exacrs12772169
Varsomers12772169
Maprs12772169
PheGenIrs12772169
hapmaprs12772169
1000 genomesrs12772169
hgdprs12772169
ensemblrs12772169
gopubmedrs12772169
geneviewrs12772169
scholarrs12772169
googlers12772169
pharmgkbrs12772169
gwascentralrs12772169
openSNPrs12772169
23andMers12772169
23andMe allrs12772169
SNP Nexus

SNPshotrs12772169
SNPdbers12772169
MSV3drs12772169
GWAS Ctlgrs12772169
GMAF0.2934
Max Magnitude
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 19578179]
Trait Acenocoumarol maintenance dosage
Title A genome-wide association study of acenocoumarol maintenance dosage
Risk Allele
P-val 8E-12
Odds Ratio NR NR


GET Evidence
rs12772169
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.277778
summary



[PMID 23089684] Similarity in recombination rate and linkage disequilibrium at CYP2C and CYP2D cytochrome P450 gene regions among Europeans indicates signs of selection and no advantage of using tagSNPs in population isolates.