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rs12918952

From SNPedia

Merged intors11545029
Orientationplus
Stabilizedplus
Make rs12918952(A;A)
Make rs12918952(A;G)
Make rs12918952(G;G)
ReferenceGRCh38 38.1/141
Chromosome16
Position78386878
GeneWWOX
is asnp
is mentioned by
dbSNPrs12918952
ebirs12918952
HLIrs12918952
Exacrs12918952
Varsomers12918952
Maprs12918952
PheGenIrs12918952
hapmaprs12918952
1000 genomesrs12918952
hgdprs12918952
ensemblrs12918952
gopubmedrs12918952
geneviewrs12918952
scholarrs12918952
googlers12918952
pharmgkbrs12918952
gwascentralrs12918952
openSNPrs12918952
23andMers12918952
23andMe allrs12918952
SNP Nexus

SNPshotrs12918952
SNPdbers12918952
MSV3drs12918952
GWAS Ctlgrs12918952
StatusMerged into rs11545029
GMAF0.3269
Max Magnitude
? (A;A) (A;G) (G;G) 28


Venter snp
Source plos
Gene Q9NZC7-8
allele A
frequency 0.621
sift TOLERATED
HuRef 1103645522665
Disease Association Defects in WWOX may be involved in esophageal squamous cell carcinoma (ESCC) (MIM:133239).



[PMID 18674750OA-icon.png] WW-domain-containing oxidoreductase is associated with low plasma HDL-C levels.


[PMID 19844255OA-icon.png] Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.


[PMID 22693020] The polymorphisms and haplotypes of WWOX gene are associated with the risk of lung cancer in southern and eastern Chinese populations.


GET Evidence
WWOX-A179T
aa_change Ala179Thr
aa_change_short A179T
impact not reviewed
qualified_impact Insufficiently evaluated not reviewed
overall_frequency 0.458468
summary



[PMID 26902998] The role of WWOX polymorphisms on COPD susceptibility and pulmonary function traits in Chinese: a case-control study and family-based analysis.


[PMID 26929649] Association of polymorphisms in WWOX gene with risk and outcome of osteosarcoma in a sample of the young Chinese population.