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rs1295686

From SNPedia

Orientationminus
Stabilizedplus
Make rs1295686(A;A)
Make rs1295686(A;G)
Make rs1295686(G;G)
ReferenceGRCh38 38.1/142
Chromosome5
Position132660151
GeneIL13
is asnp
is mentioned by
dbSNPrs1295686
ebirs1295686
HLIrs1295686
Exacrs1295686
Varsomers1295686
Maprs1295686
PheGenIrs1295686
hapmaprs1295686
1000 genomesrs1295686
hgdprs1295686
ensemblrs1295686
gopubmedrs1295686
geneviewrs1295686
scholarrs1295686
googlers1295686
pharmgkbrs1295686
gwascentralrs1295686
openSNPrs1295686
23andMers1295686
23andMe allrs1295686
SNP Nexus

SNPshotrs1295686
SNPdbers1295686
MSV3drs1295686
GWAS Ctlgrs1295686
GMAF0.388
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 20860503OA-icon.png]
Trait
Title A large-scale, consortium-based genomewide association study of asthma
Risk Allele T
P-val 1E-7
Odds Ratio 1.15 [1.09-1.20]


[PMID 21050946OA-icon.png] Does genetic regulation of IgE begin in utero? Evidence from T(H)1/T(H)2 gene polymorphisms and cord blood total IgE


[PMID 22515947OA-icon.png] Associations Between Pro- and Anti-Inflammatory Cytokine Genes and Breast Pain in Women Prior to Breast Cancer Surgery


[PMID 22075330OA-icon.png] A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study


[PMID 15660293OA-icon.png] No evidence of association or interaction between the IL4RA, IL4, and IL13 genes in type 1 diabetes.


[PMID 15726497OA-icon.png] Gene-environment interaction effects on the development of immune responses in the 1st year of life.


[PMID 16449530OA-icon.png] Cytokine polymorphisms in the Th1/Th2 pathway and susceptibility to non-Hodgkin lymphoma.


[PMID 17303794OA-icon.png] Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthma.


[PMID 17346294OA-icon.png] IL13 gene polymorphism association with cord serum immunoglobulin E.


[PMID 18056382OA-icon.png] Analysis of the 5q31 33 locus shows an association between single nucleotide polymorphism variants in the IL-5 gene and symptomatic infection with the human blood fluke, Schistosoma japonicum.


[PMID 18186920OA-icon.png] IL13 gene polymorphisms modify the effect of exposure to tobacco smoke on persistent wheeze and asthma in childhood, a longitudinal study.


[PMID 18410415OA-icon.png] Polymorphisms in the interleukin 13 and GATA binding protein 3 genes and the development of eczema during childhood.


[PMID 18625055OA-icon.png] Lack of association or interactions between the IL-4, IL-4Ralpha and IL-13 genes, and rheumatoid arthritis.


[PMID 18676870OA-icon.png] Variants in inflammation genes and the risk of biliary tract cancers and stones: a population-based study in China.


[PMID 18687755OA-icon.png] Genetic variants in T helper cell type 1, 2 and 3 pathways and gastric cancer risk in a Polish population.


[PMID 19131662OA-icon.png] A meta-analysis of candidate gene polymorphisms and ischemic stroke in 6 study populations: association of lymphotoxin-alpha in nonhypertensive patients.


[PMID 19263529OA-icon.png] Genetic risk factors in recurrent venous thromboembolism: A multilocus, population-based, prospective approach.


[PMID 19330901OA-icon.png] Association of 77 polymorphisms in 52 candidate genes with blood pressure progression and incident hypertension: the Women's Genome Health Study.


[PMID 19356949OA-icon.png] Cytokine SNPs: Comparison of allele frequencies by race and implications for future studies.


[PMID 19559392OA-icon.png] A candidate gene association study of 77 polymorphisms in migraine.


[PMID 19956101OA-icon.png] Overview of the Rapid Response data.


[PMID 19956102OA-icon.png] Evidence for association of the TCF7 locus with type I diabetes.


[PMID 19956109OA-icon.png] The Type I Diabetes Genetics Consortium 'Rapid Response' family-based candidate gene study: strategy, genes selection, and main outcome.


[PMID 20015396OA-icon.png] Innate immunity in ocular Chlamydia trachomatis infection: contribution of IL8 and CSF2 gene variants to risk of trachomatous scarring in Gambians.


[PMID 20403202OA-icon.png] Birth order modifies the effect of IL13 gene polymorphisms on serum IgE at age 10 and skin prick test at ages 4, 10 and 18: a prospective birth cohort study.


[PMID 21111021] Toll-like receptors and cytokines/cytokine receptors polymorphisms associate with non-response to hepatitis B vaccine.


[PMID 21320344OA-icon.png] Evaluation of genetic susceptibility to childhood allergy and asthma in an African American urban population.

GWAS snp
PMID [PMID 23042114]
Trait Atopic dermatitis
Title Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population.
Risk Allele T
P-val 2E-6
Odds Ratio 1.22 [NR]


[PMID 23841068OA-icon.png] Interleukin-13 +1923C/T Polymorphism Is Associated with Asthma Risk: A Meta-Analysis

GWAS snp
PMID [PMID 23886662OA-icon.png]
Trait Atopic dermatitis
Title A genome-wide association study of atopic dermatitis identifies loci with overlapping effects on asthma and psoriasis.
Risk Allele A
P-val 2E-17
Odds Ratio 1.38 [1.283-1.49]


[PMID 23028483OA-icon.png] Genome-wide association studies of asthma in population-based cohorts confirm known and suggested loci and identify an additional association near HLA.

GWAS snp
PMID [PMID 24241537]
Trait Asthma (childhood, severe)
Title A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations.
Risk Allele T
P-val 2E-6
Odds Ratio 1.31 [1.17-1.48]


[PMID 26365633] Lack of association between RAD50-IL13 polymorphisms and pediatric asthma susceptibility in Northeastern Han Chinese