|?|| (C;C) (C;T) (T;T) ||28|
is a SNP in the C20orf54
In a large study of Han Chinese esophageal cancer patients [specifically esophageal squamous cell carcinoma (ESCC)], the rs13042395(T) allele was associated with lowered risk (odds ratio 0.86, p = 1.21 x 10e-11).
In this same study , rs13042395(T) was also associated with lower risk for gastric cancer (aka stomach cancer), with an odds ratio of 0.91 (3 x 10e-3).
[PMID 22744421] Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population
[PMID 21427165] Genetic variants at 1q22 and 10q23 reproducibly associated with gastric cancer susceptibility in a Chinese population.
[PMID 22037551] A genome-wide association study identifies new susceptibility loci for non-cardia gastric cancer at 3q13.31 and 5p13.1.
[PMID 22805490] Genetic variation in C20orf54, PLCE1 and MUC1 and the risk of upper gastrointestinal cancers in Caucasian populations.