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rs13119723

From SNPedia

Orientationplus
Stabilizedplus
Make rs13119723(A;A)
Make rs13119723(A;G)
Make rs13119723(G;G)
ReferenceGRCh38 38.1/141
Chromosome4
Position122297158
GeneKIAA1109
is asnp
is mentioned by
dbSNPrs13119723
ebirs13119723
HLIrs13119723
Exacrs13119723
Varsomers13119723
Maprs13119723
PheGenIrs13119723
hapmaprs13119723
1000 genomesrs13119723
hgdprs13119723
ensemblrs13119723
gopubmedrs13119723
geneviewrs13119723
scholarrs13119723
googlers13119723
pharmgkbrs13119723
gwascentralrs13119723
openSNPrs13119723
23andMers13119723
23andMe allrs13119723
SNP Nexus

SNPshotrs13119723
SNPdbers13119723
MSV3drs13119723
GWAS Ctlgrs13119723
GMAF0.06841
Max Magnitude
? (A;A) (A;G) (G;G) 28
Of SNPs outside the HLA region, this SNP and one other (rs6822844) in the region of the IL21 gene showed the strongest association with celiac disease in a study of ~800 Caucasian patients and a meta-analysis of two further populations.[PMID 17558408OA-icon.png]


[PMID 19455118] Novel Genetic Risk Markers for Ulcerative Colitis in the IL2/IL21 Region Are in Epistasis With IL23R and Suggest a Common Genetic Background for Ulcerative Colitis and Celiac Disease

[PMID 19201773OA-icon.png] Genetic variants in the region harbouring IL2/IL21 associated with ulcerative colitis

OMIM611598
DescCELIAC DISEASE, SUSCEPTIBILITY TO, 6; CELIAC6
Variant
Relatedalso
OMIM611565
DescKIAA1109 GENE; KIAA1109
Variant
Relatedalso
[PMID 20184734OA-icon.png] The 4q27 locus and familial prostate cancer risk
GWAS snp
PMID [PMID 20453842OA-icon.png]
Trait Rheumatoid arthritis
Title Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk lock
Risk Allele A
P-val 7E-7
Odds Ratio 1.12 [NR]


[PMID 22355377OA-icon.png] Caucasian and asian specific rheumatoid arthritis risk Loci reveal limited replication and apparent allelic heterogeneity in north indians


[PMID 18311140OA-icon.png] Newly identified genetic risk variants for celiac disease related to the immune response.


[PMID 18369459OA-icon.png] A genome-wide association study of psoriasis and psoriatic arthritis identifies new disease loci.


[PMID 18418394] Association study of IL2/IL21 and FcgRIIa: significant association with the IL2/IL21 region in Scandinavian coeliac disease families.


[PMID 19061490OA-icon.png] FitSNPs: highly differentially expressed genes are more likely to have variants associated with disease.


[PMID 19176549OA-icon.png] Genome-wide association analysis by lasso penalized logistic regression.


[PMID 20553587OA-icon.png] Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.


[PMID 21304239] Analysis of IL2/IL21 gene variants in cholestatic liver diseases reveals an association with primary sclerosing cholangitis.