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rs13208776

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) normal
(A;G) normal
(G;G) higher risk for generalized vitiligo
ReferenceGRCh38 38.1/141
Chromosome6
Position168540944
GeneSMOC2
is asnp
is mentioned by
dbSNPrs13208776
ebirs13208776
HLIrs13208776
Exacrs13208776
Varsomers13208776
Maprs13208776
PheGenIrs13208776
hapmaprs13208776
1000 genomesrs13208776
hgdprs13208776
ensemblrs13208776
gopubmedrs13208776
geneviewrs13208776
scholarrs13208776
googlers13208776
pharmgkbrs13208776
gwascentralrs13208776
openSNPrs13208776
23andMers13208776
23andMe allrs13208776
SNP Nexus

SNPshotrs13208776
SNPdbers13208776
MSV3drs13208776
GWAS Ctlgrs13208776
GMAF0.1561
Max Magnitude
? (A;A) (A;G) (G;G) 28
rs13208776 is a SNP in the SPARC related modular calcium binding 2 SMOC2 gene.

A genome-wide association study (GWAS) of generalized vitiligo in 32 distantly related affected patients from a remote Romanian village identified rs13208776 as highly associated with the disorder, at an odds ratio of 7.445 (CI: 3.5-15.3, p=8x10e-8) and a population attributable risk of 28.[PMID 19890347OA-icon.png]


[PMID 20965805] SMOC2 gene variant and the risk of vitiligo in Jordanian Arabs


GET Evidence
rs13208776
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.101562
summary



[PMID 23463390] Variants in PTPN22 and SMOC2 genes and the risk of thyroid disease in the Jordanian Arab population.