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rs1321172

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) common
(C;G) 1.08x risk
(G;G) >1.08x risk
ReferenceGRCh38 38.1/141
Chromosome1
Position66265030
GenePDE4B
is asnp
is mentioned by
dbSNPrs1321172
ebirs1321172
HLIrs1321172
Exacrs1321172
Varsomers1321172
Maprs1321172
PheGenIrs1321172
hapmaprs1321172
1000 genomesrs1321172
hgdprs1321172
ensemblrs1321172
gopubmedrs1321172
geneviewrs1321172
scholarrs1321172
googlers1321172
pharmgkbrs1321172
gwascentralrs1321172
openSNPrs1321172
23andMers1321172
23andMe allrs1321172
SNP Nexus

SNPshotrs1321172
SNPdbers1321172
MSV3drs1321172
GWAS Ctlgrs1321172
GMAF0.3269
Max Magnitude
? (C;C) (C;G) (G;G) 28
rs1321172 has been reported in a large study to be associated with multiple sclerosis.

The risk allele (oriented to the dbSNP entry) is (G); the odds ratio associated with this allele is 1.08 (CI 1.02-1.14). [PMID 17660530]



GET Evidence
rs1321172
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.304688
summary



[PMID 22492128] Association of SNPs rs6498169 and rs10984447 with multiple sclerosis in Saudi patients: a model of the usefulness of familial aggregates in identifying genetic linkage in a multifactorial disease.