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rs13254738

From SNPedia

Associated with prostate cancer risk
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;C) 2 1.18x prostate cancer risk
(C;C) 2 1.18x prostate cancer risk


Make rs13254738(A;A)
ReferenceGRCh38 38.1/141
Chromosome8
Position127092098
GenePRNCR1
is asnp
is mentioned by
dbSNPrs13254738
ebirs13254738
HLIrs13254738
Exacrs13254738
Varsomers13254738
Maprs13254738
PheGenIrs13254738
hapmaprs13254738
1000 genomesrs13254738
hgdprs13254738
ensemblrs13254738
gopubmedrs13254738
geneviewrs13254738
scholarrs13254738
googlers13254738
pharmgkbrs13254738
gwascentralrs13254738
openSNPrs13254738
23andMers13254738
23andMe allrs13254738
SNP Nexus

SNPshotrs13254738
SNPdbers13254738
MSV3drs13254738
GWAS Ctlgrs13254738
GMAF0.4752
Max Magnitude2
? (A;A) (A;C) (C;C) 28
rs13254738 increases susceptibility to Prostate cancer 1.18 times for carriers of the C allele [PMID 17401364OA-icon.png]


[PMID 19549807OA-icon.png] Prostate Cancer Risk Associated Loci in African Americans



[PMID 21051319OA-icon.png] Risk of Urinary Bladder Cancer is Associated with 8q24 Variant rs9642880[T]: Results from the Los Angeles-Shanghai Case-Control Study


[PMID 22549899OA-icon.png] Genetic polymorphism and prostate cancer aggressiveness: A case-only study of 1,536 GWAS and candidate SNPs in African-Americans and European-Americans


[PMID 17618282OA-icon.png] A common genetic risk factor for colorectal and prostate cancer.


[PMID 18231127OA-icon.png] 8q24 and prostate cancer: association with advanced disease and meta-analysis.


[PMID 18360876OA-icon.png] Chromosome 8q24 markers: risk of early-onset and familial prostate cancer.


[PMID 18373104] Genetic variants in the 8q24 locus and risk of testicular germ cell tumors.


[PMID 18535017OA-icon.png] Pooled analysis of genetic variation at chromosome 8q24 and colorectal neoplasia risk.


[PMID 18577746OA-icon.png] Multiple loci with different cancer specificities within the 8q24 gene desert.


[PMID 19366828OA-icon.png] Evaluation of 8q24 and 17q risk loci and prostate cancer mortality.


[PMID 19549893OA-icon.png] Evaluation of the 8q24 prostate cancer risk locus and MYC expression.


[PMID 19602258OA-icon.png] Significance of common variants on human chromosome 8q24 in relation to the risk of prostate cancer in native Japanese men.


[PMID 19690179OA-icon.png] Functional and clinical significance of variants localized to 8q24 in colon cancer.


[PMID 20039378OA-icon.png] Estimation of genotype relative risks from pedigree data by retrospective likelihoods.


[PMID 22382457OA-icon.png] Racial disparities in the association between variants on 8q24 and prostate cancer: a systematic review and meta-analysis.


GET Evidence
rs13254738
aa_change
aa_change_short
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.419355
summary



GWAS snp
PMID [PMID 22923026OA-icon.png]
Trait Prostate cancer
Title Evaluating genetic risk for prostate cancer among Japanese and Latinos.
Risk Allele C
P-val 4E-10
Odds Ratio 1.59 [1.38-1.84]


[PMID 22848671OA-icon.png] Association of eleven common, low-penetrance colorectal cancer susceptibility genetic variants at six risk loci with clinical outcome.