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rs13293564

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(G;G) 1.63x increased nephropathy risk among type-1 diabetics
(G;T) 0 normal
(T;T) normal
ReferenceGRCh38 38.1/141
Chromosome9
Position35166766
GeneUNC13B
is asnp
is mentioned by
dbSNPrs13293564
ebirs13293564
HLIrs13293564
Exacrs13293564
Varsomers13293564
Maprs13293564
PheGenIrs13293564
hapmaprs13293564
1000 genomesrs13293564
hgdprs13293564
ensemblrs13293564
gopubmedrs13293564
geneviewrs13293564
scholarrs13293564
googlers13293564
pharmgkbrs13293564
gwascentralrs13293564
openSNPrs13293564
23andMers13293564
23andMe allrs13293564
SNP Nexus

SNPshotrs13293564
SNPdbers13293564
MSV3drs13293564
GWAS Ctlgrs13293564
GMAF0.3581
Max Magnitude0
? (G;G) (G;T) (T;T) 28
[PMID 18633107OA-icon.png] rs2281999 and rs13293564 (G/T) diabetic nephropathy type-1 diabetes case/control (1176/1323) study from 3 European populations
  • odds ratio (OR) for DN associated with the TT genotype was 1.68 [95%CI, 1.29 - 2.19], p = 1.0 10(-4))

replicated in an independent population of 412 cases and 614 controls, (combined OR of 1.63 [CI: 1.30 - 2.05], p = 2.3 10(-5))


[PMID 20687937OA-icon.png] Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus