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rs1333048

From SNPedia

coronary artery disease risk and periodontitis
Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A) 0 normal
(A;C) 2 1.3x increased coronary artery disease risk
(C;C) 2.1 1.5x increased coronary artery disease risk; 2x increased periodontitis risk
ReferenceGRCh38 38.1/141
Chromosome9
Position22125348
is asnp
is mentioned by
dbSNPrs1333048
ebirs1333048
HLIrs1333048
Exacrs1333048
Varsomers1333048
Maprs1333048
PheGenIrs1333048
hapmaprs1333048
1000 genomesrs1333048
hgdprs1333048
ensemblrs1333048
gopubmedrs1333048
geneviewrs1333048
scholarrs1333048
googlers1333048
pharmgkbrs1333048
gwascentralrs1333048
openSNPrs1333048
23andMers1333048
23andMe allrs1333048
SNP Nexus

SNPshotrs1333048
SNPdbers1333048
MSV3drs1333048
GWAS Ctlgrs1333048
GMAF0.4541
Max Magnitude2.1
? (A;A) (A;C) (C;C) 28
rs1333048 increases susceptibility to coronary artery disease 1.30 times for heterozygotes (AC) and 1.54 times for homozygotes (CC) [PMID 17478681OA-icon.png]

[PMID 19214202OA-icon.png] rs1333048 2x risk for periodontitis and a confirmation of coronary heart disease

23andMe blog

Rs1333048
PubMed [PMID 17478681OA-icon.png]
Affy Probeset SNP_A-1855630
Affy Orientation reverse
On GW 5.0 1
Alleles A/B G/T
Ancestral A
Population CEU
Allele C
Case Freq.
Control Freq.
Odds Ratio Het 1.30
Odds Ratio Hom 1.54
Odds Ratio All 1.23
Disease Coronary artery disease (CAD)


Neighborrs10757278
Distance870
Neighborrs1333049
Distance156
[PMID 20696043OA-icon.png] Replication of the association of chromosomal region 9p21.3 with generalized aggressive periodontitis (gAgP) using an independent case-control cohort
OMIM170650
Desc
Variant
Relatedalso
[PMID 22430189OA-icon.png] Replication of relevant SNPs associated with cardiovascular disease susceptibility obtained from GWAs in a case-control study in a Canarian population


[PMID 18987759OA-icon.png] Genetic testing for atherosclerosis risk: inevitability or pipe dream?


[PMID 19578366OA-icon.png] Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility.


[PMID 23587006] Validation of reported genetic risk factors for periodontitis in a large-scale replication study