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rs13357391

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) slightly earlier age at menarche
(C;T) normal
(T;T) normal
ReferenceGRCh38 38.1/141
Chromosome5
Position137105393
GeneSPOCK1
is asnp
is mentioned by
dbSNPrs13357391
ebirs13357391
HLIrs13357391
Exacrs13357391
Varsomers13357391
Maprs13357391
PheGenIrs13357391
hapmaprs13357391
1000 genomesrs13357391
hgdprs13357391
ensemblrs13357391
gopubmedrs13357391
geneviewrs13357391
scholarrs13357391
googlers13357391
pharmgkbrs13357391
gwascentralrs13357391
openSNPrs13357391
23andMers13357391
23andMe allrs13357391
SNP Nexus

SNPshotrs13357391
SNPdbers13357391
MSV3drs13357391
GWAS Ctlgrs13357391
GMAF0.2163
Max Magnitude
? (C;C) (C;T) (T;T) 28
rs13357391 is a SNP in the - get ready - "sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1" SPOCK1 gene. You gotta just love the names these fun-loving scientists come up with, don't ya?

A study of 477 Caucasian women, followed up by replication studies in another ~1,600 and also 1,300+ Chinese women, found that several linked SNPs in the SPOCK1 gene are associated with age at menarche. rs13357391 replicated across all groups studied (p < 10e-3), with the minor (C) allele associated with a (slightly) earlier age at menarche.[PMID 19282985OA-icon.png]