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rs13420827

From SNPedia

Orientationplus
Stabilizedplus
Make rs13420827(C;C)
Make rs13420827(C;G)
Make rs13420827(G;G)
ReferenceGRCh38 38.1/141
Chromosome2
Position25231099
GeneDNMT3A
is asnp
is mentioned by
dbSNPrs13420827
ebirs13420827
HLIrs13420827
Exacrs13420827
Varsomers13420827
Maprs13420827
PheGenIrs13420827
hapmaprs13420827
1000 genomesrs13420827
hgdprs13420827
ensemblrs13420827
gopubmedrs13420827
geneviewrs13420827
scholarrs13420827
googlers13420827
pharmgkbrs13420827
gwascentralrs13420827
openSNPrs13420827
23andMers13420827
23andMe allrs13420827
SNP Nexus

SNPshotrs13420827
SNPdbers13420827
MSV3drs13420827
GWAS Ctlgrs13420827
GMAF0.2144
Max Magnitude
? (C;C) (C;G) (G;G) 28
[PMID 18381459OA-icon.png] 829 Caucasian cases with primary epithelial ovarian cancer and 941 frequency-matched unaffected controls

Three SNPs in DNMT3A were associated with risk among multivitamin supplement users:

  • 3' untranslated region (UTR) C>G (rs13420827: OR, 0.8; 95% CI, 0.6-1.0; P interaction = 0.006; FPRP = 0.54)
  • intron 6 G>A (rs11887120: OR, 0.8; 95% CI, 0.7-1.0; P interaction = 0.007; FPRP = 0.57)
  • intron 22 A>T (rs11695471: OR, 1.2; 95% CI, 1.0-1.5; P interaction = 0.01; FPRP = 0.66)


[PMID 20570913OA-icon.png] Genetic variation in TYMS in the one-carbon transfer pathway is associated with ovarian carcinoma types in the Ovarian Cancer Association Consortium.