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rs140701

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 1.5 Increased risk for anxiety disorders
(A;G) 1.5 Increased risk for anxiety disorders
(G;G) 1 Normal risk for anxiety disorders
ReferenceGRCh38 38.1/142
Chromosome17
Position30211514
GeneSLC6A4
is asnp
is mentioned by
dbSNPrs140701
ebirs140701
HLIrs140701
Exacrs140701
Varsomers140701
Maprs140701
PheGenIrs140701
hapmaprs140701
1000 genomesrs140701
hgdprs140701
ensemblrs140701
gopubmedrs140701
geneviewrs140701
scholarrs140701
googlers140701
pharmgkbrs140701
gwascentralrs140701
openSNPrs140701
23andMers140701
23andMe allrs140701
SNP Nexus

SNPshotrs140701
SNPdbers140701
MSV3drs140701
GWAS Ctlgrs140701
GMAF0.4862
Max Magnitude1.5
? (A;A) (A;G) (G;G) 28

A study of patients with panic disorder or social anxiety disorder, both moderately heritable anxiety disorders, concluded that the rs140701(A) allele was associated with increased risk for both disorders. This SNP was actually part of a tightly linked haplotype A-A-G (for SNPs rs3794808, rs140701 and rs4583306, respectively) that had 1.7x increased risk for panic disorder (CI: 1.2-2.3).[PMID 18663369OA-icon.png]


[PMID 20180013] Genetic polymorphisms in folate and alcohol metabolism and breast cancer risk: a case-control study in Thai women


[PMID 20502016] Polymorphism C in the Serotonin Transporter Gene in Depression-Free Elderly Patients with Vascular Dementia


[PMID 15361494OA-icon.png] Association between a functional polymorphism in the serotonin transporter gene and diarrhoea predominant irritable bowel syndrome in women.


[PMID 16848906OA-icon.png] Genetic polymorphisms in monoamine neurotransmitter systems show only weak association with acute post-surgical pain in humans.


[PMID 17629953] Loudness dependence of auditory evoked potentials is not associated with polymorphisms or haplotypes in the serotonin transporter gene in a community-based sample of German healthy volunteers.


[PMID 19141529OA-icon.png] Serotonin transporter polymorphisms in patients with portopulmonary hypertension.


[PMID 19184136OA-icon.png] Examination of association of genes in the serotonin system to autism.


[PMID 19351213] Development and validation of a high-throughput screening method for two polymorphisms in the serotonin transporter gene.


[PMID 19772600OA-icon.png] A comparison of classification methods for predicting Chronic Fatigue Syndrome based on genetic data.


[PMID 19844206OA-icon.png] Sequence variations of ABCB1, SLC6A2, SLC6A3, SLC6A4, CREB1, CRHR1 and NTRK2: association with major depression and antidepressant response in Mexican-Americans.


[PMID 22727904] Sex determines which section of the SLC6A4 gene is linked to obsessive-compulsive symptoms in normal Chinese college students.


[PMID 26408209] Common variants of HTR1A and SLC6A4 confer the increasing risk of Schizophrenia susceptibility: A population-based association and epistasis analysis