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rs144475004

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 3.5 Significant (6x) increase in risk for psoriasis, at least in Asians
(C;G) 3.5 Signficant (6x) increase in risk for psoriasis, at least in Asians
(G;G) 0 common/normal
ReferenceGRCh38.p2 38.2/147
Chromosome17
Position80184089
GeneCARD14
is asnp
is mentioned by
dbSNPrs144475004
ebirs144475004
HLIrs144475004
Exacrs144475004
Varsomers144475004
Maprs144475004
PheGenIrs144475004
hapmaprs144475004
1000 genomesrs144475004
hgdprs144475004
ensemblrs144475004
gopubmedrs144475004
geneviewrs144475004
scholarrs144475004
googlers144475004
pharmgkbrs144475004
gwascentralrs144475004
openSNPrs144475004
23andMers144475004
23andMe allrs144475004
SNP Nexus

SNPshotrs144475004
SNPdbers144475004
MSV3drs144475004
GWAS Ctlgrs144475004
Max Magnitude3.5
rs144475004, also known as c.526G>C, p.Asp176His and D176H, represents a variant in the CARD14 gene on chromosome 17.

In 416 psoriasis patients, the rs144475004(C) allele was associated in Asian individuals with generalized pustular psoriasis (odds ratio 6.4, p=8.4×10e-5), but no CARD14 mutations were found to be associated with other forms of psoriasis vulgaris (PV) or with pityriasis rubra pilaris (PRP).[PMID 26203641]