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rs1517114

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common in clinvar
Make rs1517114(C;G)
Make rs1517114(G;G)
ReferenceGRCh38 38.1/141
Chromosome8
Position68476982
GeneC8orf34
is asnp
is mentioned by
dbSNPrs1517114
ebirs1517114
HLIrs1517114
Exacrs1517114
Varsomers1517114
Maprs1517114
PheGenIrs1517114
hapmaprs1517114
1000 genomesrs1517114
hgdprs1517114
ensemblrs1517114
gopubmedrs1517114
geneviewrs1517114
scholarrs1517114
googlers1517114
pharmgkbrs1517114
gwascentralrs1517114
openSNPrs1517114
23andMers1517114
23andMe allrs1517114
SNP Nexus

SNPshotrs1517114
SNPdbers1517114
MSV3drs1517114
GWAS Ctlgrs1517114
GMAF0.314
Max Magnitude0
? (C;C) (C;G) (G;G) 28
GWAS snp
PMID [PMID 22664479]
Trait
Title A genome-wide association study for irinotecan-related severe toxicities in patients with advanced non-small-cell lung cancer.
Risk Allele C
P-val 0.000009
Odds Ratio 4.1000 None


ClinVar
Risk rs1517114(G;G)
Alt rs1517114(G;G)
Reference rs1517114(C;C)
Significance Drug-response
Disease irinotecan response - Toxicity/ADR
Variation info
Gene C8orf34
CLNDBN irinotecan response - Toxicity/ADR
Reversed 0
HGVS NC_000008.10:g.69389217C>G
CLNSRC PharmGKB Clinical Annotation PharmGKB
CLNACC RCV000211148.1,