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rs1530057

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(C;C) 0 common in complete genomics
Make rs1530057(A;A)
Make rs1530057(A;C)
ReferenceGRCh38 38.1/141
Chromosome3
Position29533972
GeneRBMS3
is asnp
is mentioned by
dbSNPrs1530057
ebirs1530057
HLIrs1530057
Exacrs1530057
Varsomers1530057
Maprs1530057
PheGenIrs1530057
hapmaprs1530057
1000 genomesrs1530057
hgdprs1530057
ensemblrs1530057
gopubmedrs1530057
geneviewrs1530057
scholarrs1530057
googlers1530057
pharmgkbrs1530057
gwascentralrs1530057
openSNPrs1530057
23andMers1530057
23andMe allrs1530057
SNP Nexus

SNPshotrs1530057
SNPdbers1530057
MSV3drs1530057
GWAS Ctlgrs1530057
GMAF0.04591
Max Magnitude0
? (A;A) (A;C) (C;C) 28
GWAS snp
PMID [PMID 19654303OA-icon.png]
Trait Lung cancer
Title Deciphering the Impact of Common Genetic Variation on Lung Cancer Risk: A Genome-Wide Association Study
Risk Allele
P-val 0.000003
Odds Ratio 1.26 [NR]


[PMID 21303977OA-icon.png] Genome-wide significant association between a sequence variant at 15q15.2 and lung cancer risk.

In this study, we sought to confirm 7 variants with suggestive association to lung cancer (P < 10(-5)) in a recently published meta-analysis. In a GWA dataset of 1,447 lung cancer cases and 36,256 controls in Iceland, 3 correlated variants on 15q15.2 (rs504417, rs11853991, and rs748404) showed a significant association with lung cancer, whereas rs4254535 on 2p14, rs1530057 on 3p24.1, rs6438347 on 3q13.31, and rs1926203 on 10q23.31 did not.


GET Evidence
rs1530057
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.0234375
summary