Have questions? Visit https://www.reddit.com/r/SNPedia

rs1532085

From SNPedia

Orientationplus
Stabilizedplus
Make rs1532085(A;A)
Make rs1532085(A;G)
Make rs1532085(G;G)
ReferenceGRCh38 38.1/141
Chromosome15
Position58391167
GeneLOC102724766
is asnp
is mentioned by
dbSNPrs1532085
ebirs1532085
HLIrs1532085
Exacrs1532085
Varsomers1532085
Maprs1532085
PheGenIrs1532085
hapmaprs1532085
1000 genomesrs1532085
hgdprs1532085
ensemblrs1532085
gopubmedrs1532085
geneviewrs1532085
scholarrs1532085
googlers1532085
pharmgkbrs1532085
gwascentralrs1532085
openSNPrs1532085
23andMers1532085
23andMe allrs1532085
SNP Nexus

SNPshotrs1532085
SNPdbers1532085
MSV3drs1532085
GWAS Ctlgrs1532085
GMAF0.4458
Max Magnitude
? (A;A) (A;G) (G;G) 28
GWAS snp
PMID [PMID 19060911OA-icon.png]
Trait Cholesterol, total
Title Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts
Risk Allele G
P-val 4E-7
Odds Ratio 0.05 [NR] SD decrease
GWAS snp
PMID [PMID 19060910OA-icon.png]
Trait HDL cholesterol
Title Genome-wide association analysis of metabolic traits in a birth cohort from a founder population
Risk Allele A
P-val 2E-10
Odds Ratio 0.05 [0.03-0.06] mmol/l increase





OMIM612797
Desc
Variant
Relatedalso
[PMID 21867541OA-icon.png] Evaluation of the global association between cholesterol-associated polymorphisms and Alzheimer's disease suggests a role for rs3846662 and HMGCR splicing in disease risk
GWAS snp
PMID [PMID 20686565OA-icon.png]
Trait
Title Biological, clinical and population relevance of 95 loci for blood lipids.
Risk Allele A
P-val 0
Odds Ratio 1.4500 None
GWAS snp
PMID [PMID 22399527OA-icon.png]
Trait
Title Genome-wide screen for metabolic syndrome susceptibility Loci reveals strong lipid gene contribution but no evidence for common genetic basis for clustering of metabolic syndrome traits.
Risk Allele G
P-val 5E-24
Odds Ratio 0.1300 None


[PMID 19041386OA-icon.png] Genetic-epidemiological evidence on genes associated with HDL cholesterol levels: a systematic in-depth review.


[PMID 19936222OA-icon.png] Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis.


[PMID 19951432OA-icon.png] Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.


[PMID 20502693OA-icon.png] Genetics and beyond--the transcriptome of human monocytes and disease susceptibility.


GET Evidence
rs1532085
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.5625
summary



GWAS snp
PMID [PMID 23222517OA-icon.png]
Trait Red blood cell traits
Title Seventy-five genetic loci influencing the human red blood cell.
Risk Allele G
P-val 7E-11
Odds Ratio .03 [0.022-0.046] unit increase
GWAS snp
PMID [PMID 22916037OA-icon.png]
Trait Metabolite levels
Title Novel Loci for metabolic networks and multi-tissue expression studies reveal genes for atherosclerosis.
Risk Allele
P-val 9E-104
Odds Ratio NR NR
GWAS snp
PMID [PMID 24097068OA-icon.png]
Trait Cholesterol, total
Title Discovery and refinement of loci associated with lipid levels.
Risk Allele A
P-val 7E-47
Odds Ratio .05 [NR] unit increase