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rs1535

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(A;A)
(A;G) 4+ IQ points for breastfeeding
(G;G) 0 normal
ReferenceGRCh38 38.1/141
Chromosome11
Position61830500
GeneFADS2
is asnp
is mentioned by
dbSNPrs1535
ebirs1535
HLIrs1535
Exacrs1535
Varsomers1535
Maprs1535
PheGenIrs1535
hapmaprs1535
1000 genomesrs1535
hgdprs1535
ensemblrs1535
gopubmedrs1535
geneviewrs1535
scholarrs1535
googlers1535
pharmgkbrs1535
gwascentralrs1535
openSNPrs1535
23andMers1535
23andMe allrs1535
SNP Nexus

SNPshotrs1535
SNPdbers1535
MSV3drs1535
GWAS Ctlgrs1535
GMAF0.3494
Max Magnitude0
? (A;A) (A;G) (G;G) 28
[PMID 17984066OA-icon.png] 4+ IQ points for breastfeeding with the AA or AG genotypes
GWAS snp
PMID [PMID 20339536OA-icon.png]
Trait Response to statin therapy
Title Genome-wide association of lipid-lowering response to statins in combined study populations
Risk Allele G
P-val 0.000007
Odds Ratio None None

[PMID 20644632OA-icon.png] FADS2 Polymorphisms Modify the Effect of Breastfeeding on Child IQ

GWAS snp
PMID [PMID 20694148OA-icon.png]
Trait
Title A genome-wide association study of the metabolic syndrome in Indian Asian men
Risk Allele G
P-val 4E-7
Odds Ratio 0.03 [0.02-0.04] mmol/l decrease
GWAS snp
PMID [PMID 21829377OA-icon.png]
Trait
Title Genetic Loci Associated with Plasma Phospholipid n-3 Fatty Acids: A Meta-Analysis of Genome-Wide Association Studies from the CHARGE Consortium.
Risk Allele A
P-val 0
Odds Ratio 0.0700 [NR] % increase


[PMID 19060910OA-icon.png] Genome-wide association analysis of metabolic traits in a birth cohort from a founder population.


[PMID 19798445OA-icon.png] Genetic determinants of circulating sphingolipid concentrations in European populations.


[PMID 21347282OA-icon.png] Genome-wide association study of coronary heart disease and its risk factors in 8,090 African Americans: the NHLBI CARe Project.


[PMID 22194195OA-icon.png] Polyunsaturated fatty acid levels in blood during pregnancy, at birth and at 7 years: their associations with two common FADS2 polymorphisms.

Breastfeeding and IQ


[PMID 23861364OA-icon.png] Do Genetic Modifiers of HDL-C and Triglyceride Levels also Modify Their Response to a Lifestyle Intervention in the Setting of Obesity and Type-2 Diabetes Mellitus? The Look AHEAD Study


[PMID 22743310OA-icon.png] Circulating and dietary alpha-linolenic acid and incidence of congestive heart failure in older adults: the Cardiovascular Health Study.


[PMID 23636240] FADS genotype and diet are important determinants of DHA status: a cross-sectional study in Danish infants.


[PMID 23737301] A prospective study of the effects of breastfeeding and FADS2 polymorphisms on cognition and hyperactivity/attention problems.