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rs1564282

From SNPedia

Orientationplus
Stabilizedplus
Geno Mag Summary
(C;C) 0 common on affy axiom data
Make rs1564282(C;T)
Make rs1564282(T;T)
ReferenceGRCh38 38.1/141
Chromosome4
Position858525
GeneGAK
is asnp
is mentioned by
dbSNPrs1564282
ebirs1564282
HLIrs1564282
Exacrs1564282
Varsomers1564282
Maprs1564282
PheGenIrs1564282
hapmaprs1564282
1000 genomesrs1564282
hgdprs1564282
ensemblrs1564282
gopubmedrs1564282
geneviewrs1564282
scholarrs1564282
googlers1564282
pharmgkbrs1564282
gwascentralrs1564282
openSNPrs1564282
23andMers1564282
23andMe allrs1564282
SNP Nexus

SNPshotrs1564282
SNPdbers1564282
MSV3drs1564282
GWAS Ctlgrs1564282
GMAF0.08356
Max Magnitude0
? (C;C) (C;T) (T;T) 28
GWAS snp
PMID [PMID 18985386OA-icon.png]
Trait Parkinson disease (familial)
Title Genomewide association study for susceptibility genes contributing to familial Parkinson disease
Risk Allele T
P-val 7E-7
Odds Ratio 1.70 [NR]



[PMID 21058943OA-icon.png] Replication of GWAS associations for GAK and MAPT in Parkinson's disease


[PMID 22198721] GWAS-linked GAK locus in Parkinson's disease in Han Chinese and meta-analysis


[PMID 21258085OA-icon.png] Cyclin-G-associated kinase modifies alpha-synuclein expression levels and toxicity in Parkinson's disease: results from the GenePD Study.


[PMID 21281506OA-icon.png] A unified framework for multi-locus association analysis of both common and rare variants.


GET Evidence
rs1564282
aa_change
aa_change_short
impact pathogenic
qualified_impact Insufficiently evaluated pathogenic
overall_frequency 0.0546875
summary



[PMID 23826309OA-icon.png] Genetic Variations of GAK in Two Chinese Parkinson's Disease Populations: A Case-Control Study


[PMID 23618683] GAK rs1564282 and DGKQ rs11248060 increase the risk for Parkinson's disease in a Chinese population.