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rs16139

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs16139(A;G)
Make rs16139(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position24285260
GeneNPY
is asnp
is mentioned by
dbSNPrs16139
ebirs16139
HLIrs16139
Exacrs16139
Varsomers16139
Maprs16139
PheGenIrs16139
hapmaprs16139
1000 genomesrs16139
hgdprs16139
ensemblrs16139
gopubmedrs16139
geneviewrs16139
scholarrs16139
googlers16139
pharmgkbrs16139
gwascentralrs16139
openSNPrs16139
23andMers16139
23andMe allrs16139
SNP Nexus

SNPshotrs16139
SNPdbers16139
MSV3drs16139
GWAS Ctlgrs16139
GMAF0.01745
Max Magnitude0
? (A;A) (A;G) (G;G) 28
OMIM162640
DescNEUROPEPTIDE Y POLYMORPHISM
Variant0001
Relatedalso



ClinVar
Risk rs16139(G,T;G,T)
Alt rs16139(G,T;G,T)
Reference rs16139(A;A)
Significance Non-pathogenic
Disease NEUROPEPTIDE Y POLYMORPHISM
Variation info
Gene NPY
CLNDBN NEUROPEPTIDE Y POLYMORPHISM
Reversed 1
HGVS NC_000007.13:g.24324879T>C
CLNSRC OMIM Allelic Variant
CLNACC RCV000015068.2,



[PMID 17357083OA-icon.png] Medical sequencing at the extremes of human body mass.

[PMID 18385673OA-icon.png] Genetic variation in human NPY expression affects stress response and emotion.

[PMID 18828811OA-icon.png] Neuropeptide Y receptor genes are associated with alcohol dependence, alcohol withdrawal phenotypes, and cocaine dependence.

[PMID 19119412OA-icon.png] Neuropeptide Y gene polymorphisms confer risk of early-onset atherosclerosis.

[PMID 19470168OA-icon.png] NPAS2 and PER2 are linked to risk factors of the metabolic syndrome.

[PMID 19587357OA-icon.png] A systematic meta-analysis of genetic association studies for diabetic retinopathy.

[PMID 20180986OA-icon.png] CLOCK is suggested to associate with comorbid alcohol use and depressive disorders.

[PMID 20351714] Poor replication of candidate genes for major depressive disorder using genome-wide association data.


GET Evidence
NPY-L7P
aa_change Leu7Pro
aa_change_short L7P
impact pharmacogenetic
qualified_impact Insufficiently evaluated pharmacogenetic
overall_frequency 0.0276074
summary



[PMID 22290120OA-icon.png] The evolutionary significance of depression in Pathogen Host Defense (PATHOS-D).


[PMID 23122776] Neuropeptide Y polymorphism increases the risk for asthma in overweight subjects; protection from atherosclerosis in asthmatic subjects--the cardiovascular risk in young Finns study.


[PMID 25221996OA-icon.png] Association of Neuropeptide Y (NPY), Interleukin-1B (IL1B) Genetic Variants and Correlation of IL1B Transcript Levels with Vitiligo Susceptibility


[PMID 27559040] Association study of two functional single nucleotide polymorphisms of neuropeptide y gene with multiple sclerosis.