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rs16147

From SNPedia

Orientationminus
Stabilizedminus
Make rs16147(A;A)
Make rs16147(A;G)
Make rs16147(G;G)
ReferenceGRCh38 38.1/141
Chromosome7
Position24283791
GeneNPY
is asnp
is mentioned by
dbSNPrs16147
ebirs16147
HLIrs16147
Exacrs16147
Varsomers16147
Maprs16147
PheGenIrs16147
hapmaprs16147
1000 genomesrs16147
hgdprs16147
ensemblrs16147
gopubmedrs16147
geneviewrs16147
scholarrs16147
googlers16147
pharmgkbrs16147
gwascentralrs16147
openSNPrs16147
23andMers16147
23andMe allrs16147
SNP Nexus

SNPshotrs16147
SNPdbers16147
MSV3drs16147
GWAS Ctlgrs16147
GMAF0.4449
Max Magnitude
? (A;A) (A;G) (G;G) 28
[PMID 18385673OA-icon.png] located in the promoter region alters NPY expression in vitro and seems to account for more than half of the variation in expression in vivo. These convergent findings are consistent with the function of NPY as an anxiolytic peptide and help to explain inter-individual variation in resiliency to stress, a risk factor for many diseases.

[PMID 19119412OA-icon.png] Risk of Early-Onset atherosclerosis

OMIM162640
DescNEUROPEPTIDE Y; NPY
Variant
Relatedalso
[PMID 20037921OA-icon.png] NPY moderates the relation between hurricane exposure and generalized anxiety disorder in an epidemiologic sample of hurricane-exposed adults


[PMID 22584873] Genetic Variation in the Neuropeptide Y Gene Promoter Is Associated with Increased Risk of Tobacco Smoking


[PMID 22669627OA-icon.png] Polymorphisms in LEP and NPY genes modify the response to soluble fibre Plantago ovata husk intake on cardiovascular risk biomarkers


[PMID 19566775] Association between neuropeptide Y gene and its receptor Y1 gene and methamphetamine dependence.


[PMID 19854625] Neuropeptide Y (NPY) gene: Impact on emotional processing and treatment response in anxious depression.


[PMID 20435026] Age and sex dependent genetic effects of neuropeptide Y promoter polymorphism on susceptibility to ischemic stroke in Koreans.


[PMID 20648632OA-icon.png] Human NPY promoter variation rs16147:T>C as a moderator of prefrontal NPY gene expression and negative affect.


[PMID 21273004] An interaction between a neuropeptide Y gene polymorphism and early adversity modulates endocrine stress responses.


[PMID 22966009OA-icon.png] Neuropeptide Y Promoter Polymorphism Modifies Effects of a Weight-Loss Diet on 2-Year Changes of Blood Pressure: The Preventing Overweight Using Novel Dietary Strategies Trial


[PMID 23277265] Association of a Functional Polymorphism in Neuropeptide Y With Antipsychotic-Induced Weight Gain in Schizophrenia Patients


[PMID 23652383] Functional Polymorphism in the Neuropeptide Y Gene Promoter (rs16147) Is Associated with Serum Leptin Levels and Waist-Hip Ratio in Women


[PMID 22941950] Increasing association between a neuropeptide Y promoter polymorphism and body mass index during the course of development.


[PMID 23122776] Neuropeptide Y polymorphism increases the risk for asthma in overweight subjects; protection from atherosclerosis in asthmatic subjects--the cardiovascular risk in young Finns study.


[PMID 23624317] Influence of variants in the NPY gene on obesity and metabolic syndrome features in Spanish children.


[PMID 24897239] Association of neuropeptide Y gene rs16147 polymorphism with metabolic syndrome in patients with documented coronary artery disease


[PMID 25081719] Association of Polymorphisms in Stress-Related TNFα and NPY Genes with the Metabolic Syndrome in Han and Hui Ethnic Groups


[PMID 25221996OA-icon.png] Association of Neuropeptide Y (NPY), Interleukin-1B (IL1B) Genetic Variants and Correlation of IL1B Transcript Levels with Vitiligo Susceptibility


[PMID 25427865] Lack of an Association between a Functional Polymorphism in the Neuropeptide Y Gene Promoter and the Presence of Coronary Artery Disease in an Iranian Population


[PMID 26156739] Neuropeptide Y genotype, central obesity, and abdominal fat distribution: the POUNDS LOST trial


[PMID 27469060] Neuropeptide Y associated with asthma in young adults.


[PMID 27559040] Association study of two functional single nucleotide polymorphisms of neuropeptide y gene with multiple sclerosis.