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rs16754

From SNPedia

Orientationminus
Stabilizedminus
Geno Mag Summary
(A;A) 0 common in clinvar
Make rs16754(A;G)
Make rs16754(G;G)
ReferenceGRCh38 38.1/141
Chromosome11
Position32396399
GeneWT1
is asnp
is mentioned by
dbSNPrs16754
ebirs16754
HLIrs16754
Exacrs16754
Varsomers16754
Maprs16754
PheGenIrs16754
hapmaprs16754
1000 genomesrs16754
hgdprs16754
ensemblrs16754
gopubmedrs16754
geneviewrs16754
scholarrs16754
googlers16754
pharmgkbrs16754
gwascentralrs16754
openSNPrs16754
23andMers16754
23andMe allrs16754
SNP Nexus

SNPshotrs16754
SNPdbers16754
MSV3drs16754
GWAS Ctlgrs16754
GMAF0.3223
Max Magnitude0
? (A;A) (A;G) (G;G) 28

[PMID 20038731] Single Nucleotide Polymorphism in the Mutational Hotspot of WT1 Predicts a Favorable Outcome in Patients With Cytogenetically Normal Acute Myeloid Leukemia


[PMID 20368538] Impact of IDH1 R132 Mutations and an IDH1 Single Nucleotide Polymorphism in Cytogenetically Normal Acute Myeloid Leukemia: SNP rs11554137 Is an Adverse Prognostic Factor

[PMID 21189390OA-icon.png] WT1 Synonymous SNP rs16754 Correlates With Higher mRNA Expression and Predicts Significantly Improved Outcome in Favorable-Risk Pediatric Acute Myeloid Leukemia: A Report From the Children's Oncology Group


[PMID 21372155] Integrative prognostic risk score in acute myeloid leukemia with normal karyotype


[PMID 21659357OA-icon.png] Clinical outcome and gene- and microRNA-expression profiling according to the Wilms tumor 1 (WT1) single nucleotide polymorphism rs16754 in adult de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study


[PMID 22015946] Single nucleotide polymorphism of Wilms' tumor 1 gene rs16754 in Korean patients with cytogenetically normal acute myeloid leukemia


[PMID 22506617] WT1 Mutations and Single Nucleotide Polymorphism rs16754 Analysis of Patients with Pediatric Acute Myeloid Leukemia in a Chinese Population


[PMID 22568493] ID1 expression associates with other molecular markers and is not an independent prognostic factor in cytogenetically normal acute myeloid leukaemia

[PMID 15687485] Variants in the Wilms' tumor gene are associated with focal segmental glomerulosclerosis in the African American population.

[PMID 17267408OA-icon.png] Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.

[PMID 19914700] Single-nucleotide polymorphism in WT1 gene in a hyperplastic intralobar nephrogenic rest with botryoid protrusion.

[PMID 20644087] No prognostic impact of the WT1 gene single nucleotide polymorphism rs16754 in pediatric acute myeloid leukemia.

[PMID 21760594] Wilms' tumor 1 single-nucleotide polymorphism rs16754 does not predict clinical outcome in adult acute myeloid leukemia.

[PMID 21798259] WT1 mutations and polymorphisms in Southeast Asian acute myeloid leukemia.


[PMID 23484026OA-icon.png] Single Nucleotide Polymorphisms in the Wilms' Tumour Gene 1 in Clear Cell Renal Cell Carcinoma


[PMID 23956224] The prognostic effect of high diagnostic WT1 gene expression in pediatric AML depends on WT1 SNP rs16754 status: Report from the Children's Oncology Group


[PMID 22895555] Analysis of mutational status, SNP rs16754, and expression levels of Wilms tumor 1 (WT1) gene in acute promyelocytic leukemia.


[PMID 23070125] Analysis of SNP rs16754 of WT1 gene in a series of de novo acute myeloid leukemia patients.


[PMID 23117548] WT1, WTX and CTNNB1 mutation analysis in 43 patients with sporadic Wilms' tumor.


[PMID 26046002OA-icon.png] Association between WT1 polymorphisms and susceptibility to breast cancer: results from a case-control study in a southwestern Chinese population


[PMID 26224397] Wilms tumor gene single nucleotide polymorphism rs16754 predicts a favorable outcome in children with acute lymphoblastic leukemia


[PMID 26499507] The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia


ClinVar
Risk rs16754(G;G)
Alt rs16754(G;G)
Reference rs16754(A;A)
Significance Non-pathogenic
Disease not specified
Variation info
Gene WT1
CLNDBN not specified
Reversed 1
HGVS NC_000011.9:g.32417945T>C
CLNSRC
CLNACC RCV000179975.1,



[PMID 27801325] [Association of WT1 rs16754 polymorphism with clinical features and prognosis in patients with acute myeloid leukemia].